Hormone-Based Treatments in Subfertile Males

Subfertility is defined as the condition of being less than normally fertile though still capable of effecting fertilization. When these subfertile couples seek assistance for conception, a thorough evaluation of male endocrine function is often overlooked. Spermatogenesis is a complex process where even subtle alterations in this process can lead to subfertility or infertility. Male endocrine abnormalities may suggest a specific diagnosis contributing to subfertility; however, in many patients, the underlying etiology is still unknown. Optimizing underlying endocrine abnormalities may improve spermatogenesis and fertility. This manuscript reviews reproductive endocrine abnormalities and hormone-based treatments.

Current urology reports. 2016 Aug [Epub]

Darshan P Patel, Jason C Chandrapal, James M Hotaling

Division of Urology, Department of Surgery, University of Utah Health Care, 30 N 1900 E, Rm 3B420, Salt Lake City, UT, 84132, USA., Division of Urology, Department of Surgery, University of Utah Health Care, 30 N 1900 E, Rm 3B420, Salt Lake City, UT, 84132, USA. ., Division of Urology, Department of Surgery, University of Utah Health Care, 30 N 1900 E, Rm 3B420, Salt Lake City, UT, 84132, USA.

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