Background Infertility and problems of impaired fecundity have been a concern through the ages and are also considerable clinical problems today, affecting many couples worldwide. Most infertility cases are primarily attributed to male factors, which play a significant role. Additionally, a substantial number of these patients exhibit suboptimal sperm parameters. The study is mainly designed for individual intervention and outcome. We aim to evaluate the demographics, etiology, utilization of treatments, and outcomes of males undergoing infertility treatment. Methodology We retrospectively enrolled infertile couples from January 2021 to March 2023, covering the past two years. All patients were evaluated and investigated per the study protocol to identify the cause of infertility. Results Two thousand three hundred forty-eight males were enrolled in the study, of whom 1,484 (63%) were found to have a standard semen analysis. A total of 868 (37%) had abnormal semen parameters. Two hundred and seventy-two (12%) patients completed the evaluation. All parameters, except for hypospermia, displayed lower percentages of motility compared to normozospermia. All semen parameters, except for hypospermia, showed a significantly lower normal morphology in comparison to normozospermia. This reduction increased by 10% for each year of age increment. Conclusions The study concluded by following a protocol for evaluating male patients. If an abnormal sperm parameter is identified before considering intracytoplasmic sperm injection (ICSI), it is recommended to conduct at least karyotyping and microdeletion analysis on the Y-chromosome's q arm.
Cureus. 2023 Sep 20*** epublish ***
Sumesh Choudhary, Vineet Mishra, Pritti Kumari, Hardik Sheth, Rahnuma Ahmad, Mainul Haque, Santosh Kumar
Department of Obstetrics and Gynecology, Smt. G. R. Doshi and Smt. K. M. Mehta Institute of Kidney Diseases and Research Center and Dr. H. L. Trivedi Institute of Transplantation Sciences, Ahmedabad, IND., Department of Obstetrics and Gynecology Genetics, Smt. G. R. Doshi and Smt. K. M. Mehta Institute of Kidney Diseases and Research Center and Dr. H. L. Trivedi Institute of Transplantation Sciences, Ahmedabad, IND., Department of Physiology, Medical College for Women and Hospital, Dhaka, BGD., Department of Research, Karnavati Scientific Research Center (KSRC) Karnavati School of Dentistry, Karnavati University, Gandhinagar, IND., Department of Periodontology and Implantology, Karnavati School of Dentistry, Karnavati University, Gandhinagar, IND.