Testosterone has a variety of functions and is commonly used in older men to treat symptoms of hypogonadism, such as decreased libido, decreased mood and erectile dysfunction. Despite its positive effects on sexual function, it has a negative effect on fertility. Exogenous testosterone therapy can negatively affect the hypothalamic-pituitary gonadal axis and inhibit the production of follicle stimulating hormone and luteinizing hormone. The purpose of this review is to discuss the contraceptive properties of testosterone therapy and to discuss strategies to increase testosterone in men with the desire to preserve fertility.
The world journal of men's health. 2018 Oct 10 [Epub ahead of print]
Amir Shahreza Patel, Joon Yau Leong, Libert Ramos, Ranjith Ramasamy
Department of Urology, University of Miami Miller School of Medicine, Miami, FL, USA. ., Department of Urology, Thomas Jefferson University, Philadelphia, PA, USA., Department of Urology, University of Miami Miller School of Medicine, Miami, FL, USA.