In several studies of patients with type 2 diabetes mellitus, a positive association between depressive symptoms and erectile dysfunction (ED) has been reported. No evidence exists, however, regarding the association between depressive symptoms and ED among Japanese patients with type 2 diabetes mellitus. Thus, we examined this issue among Japanese patients with type 2 diabetes mellitus. Study subjects were 469 male Japanese patients with type 2 diabetes mellitus, aged 19 years or over. ED, moderate to severe ED and severe ED were defined as present when a subject had a Sexual Health Inventory for Men score <22, <12 and <8, respectively. Depressive symptoms were defined as present when a subject had a Self-Rating Depression Scale (SDS) score >49. Adjustment was made for age, body mass index, waist, duration of type 2 diabetes, current smoking, current drinking, hypertension, dyslipidemia, coronary artery disease, stroke, glycated hemoglobin and diabetic neuropathy. The prevalence values of depressive symptoms, moderate to severe ED and severe ED were 15.1%, 64.2% and 51.0%, respectively. Depressive symptoms were independently positively associated with moderate to severe ED and severe ED (adjusted odds ratios were 2.23 (95% confidence interval (CI): 1.17-4.43) and 1.86 (95% CI: 1.04-3.41), respectively). In Japanese patients with type 2 diabetes mellitus, depressive symptoms may be associated with ED.International Journal of Impotence Research advance online publication, 17 November 2016; doi:10.1038/ijir.2016.45.
International journal of impotence research. 2016 Nov 17 [Epub ahead of print]
S Furukawa, T Sakai, T Niiya, H Miyaoka, T Miyake, S Yamamoto, K Maruyama, T Ueda, H Senba, M Torisu, H Minami, M Onji, T Tanigawa, B Matsuura, Y Hiasa, Y Miyake
Department of Epidemiology and Preventive Medicine, Ehime University Graduate School of Medicine, Toon, Japan., Department of Internal Medicine, Yawatahama General City Hospital, Yawatahama, Japan., Department of Internal Medicine, Matsuyama Shimin Hospital, Matsuyama, Japan., Department of Internal Medicine, Saiseikai Matsuyama Hospital, Matsuyama, Japan., Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Japan., Department of Lifestyle-related Medicine and Endocrinology, Ehime University Graduate School of Medicine, Toon, Japan., Department of Public Health, Juntendo University School of Medicine, Bunkyo, Japan., Department of Internal Medicine, Ehime Prefectural Central Hospital, Matuayama, Japan., Department of Internal Medicine, Saiseikai Saijo Hospital, Saijo, Japan., Department of Internal Medicine, Ehime Niihama Hospital, Niihama, Japan., Department of Internal Medicine, Saiseikai Imabari Hospital, Imabari, Japan.