Prevalence and Associated Factors of Erectile Dysfunction in Patients With Moderate to Severe Psoriasis and Healthy Population: A Comparative Study Considering Physical and Psychological Factors

Recent studies have shown that psoriasis is associated with an increased prevalence of erectile dysfunction. To our knowledge, no comparative study has considered simultaneously the role of organic factors and psychological factors in this process. We performed a prospective case series study matched by age to explore the prevalence of erectile dysfunction in psoriasis patients compared to a healthy population and to investigate the role of anxiety, depression, and cardiovascular risk factors in the relationship between psoriasis and erectile dysfunction. The healthy group was matched by frequency to cases by age. Seventy-nine patients with moderate to severe psoriasis and 79 healthy controls participated in the study. Participants completed the Massachusetts General Hospital Sexual Functioning Questionnaire and the Hospital Anxiety and Depression Scale. Psoriasis patients had an increased prevalence of erectile dysfunction in comparison to controls, 34.2 vs. 17.7 % (p < .05). Multivariate analysis showed a significant association between erectile dysfunction and age, smoking and anxiety/depression, but not with psoriasis per se. In conclusion, the higher prevalence of smoking and anxiety/depression among patients with moderate to severe psoriasis probably explains the higher prevalence of erectile dysfunction in this population.

Archives of sexual behavior. 2016 Jun 07 [Epub ahead of print]

Alejandro Molina-Leyva, Ignacio Molina-Leyva, Ana Almodovar-Real, Jose Carlos Ruiz-Carrascosa, Ramon Naranjo-Sintes, Jose Juan Jimenez-Moleon

Department of Dermatology, Complejo Hospitalario Torrecárdenas, Almeria, Spain. ., Department of Preventive Medicine and Public Health, University of Granada, Granada, Spain., Department of Dermatology, Hospital Santa Ana, Granada, Spain., Department of Dermatology, Complejo Hospitalario Universitario Granada, Avenida Doctor Oloriz 16, 18012, Granada, Spain., Department of Dermatology, Complejo Hospitalario Universitario Granada, Avenida Doctor Oloriz 16, 18012, Granada, Spain., Department of Preventive Medicine and Public Health, University of Granada, Granada, Spain.

E-Newsletters

Newsletter subscription

Free Daily and Weekly newsletters offered by content of interest

The fields of GU Oncology and Urology are rapidly advancing. Sign up today for articles, videos, conference highlights and abstracts from peer-review publications by disease and condition delivered to your inbox and read on the go.

Subscribe