Metabolic syndrome and peripheral artery disease: Two related conditions

To ascertain the prevalence of metabolic syndrome (MS) in patients with peripheral artery disease (PAD) at the Martorell primary care (PC) center. To analyze the differences in comorbidities and cardiovascular risk factors between patients with PAD with and without MS.

A cross-sectional, descriptive study on patients diagnosed with PAD according to computerized clinical records of the Martorell PC center. Variables collected included age, sex, high blood pressure (HBP), dyslipidemia (DLP), diabetes (DM), smoking, obesity, cardiovascular disease (CVD), erectile dysfunction (ED), renal failure (RF), and oligoalbuminuria. An analysis comparing patients with and without MS was performed.

There were 131 patients diagnosed with PAD, 104 (79%) of whom were male. Sixty-three (48.1%) also had MS. Patients with both PAD and MS had, as compared to those with PAD only, a higher prevalence of HBP (87.3 vs. 60.3%, P: 0.001), DLP (77.8 vs. 60.3%, P: 0.03), DM (69.8 vs. 30.9%, P<.001), obesity (25.4 vs. 10.3%, P: 0.03), CVD (42.9 vs. 19.1%); P: 0.004), ED (81.3 vs. 54.3%, P: 0.02), and RF (40.3 vs. 17.9%, P: 0.006).

Patients with both PAD and MS had a higher prevalence of HBP, DLP, DM, and obesity. They also had more cardiovascular events and were significantly associated with pathological conditions highly relevant for cardiovascular prognosis such as erectile dysfunction and chronic kidney disease.

Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion. 2016 May 07 [Epub ahead of print]

Pilar Ángeles Oriol Torón, Teresa Badía Farré, Amparo Romaguera Lliso, Jovita Roda Diestro

Medicina Familiar y Comunitaria, ABS de Martorell, Barcelona, España. Electronic address: ., Medicina Familiar y Comunitaria, ABS de Martorell, Barcelona, España., Departament de Metodología, Qualitat i Avaluació Assistencial, AP Costa de Ponent, Institut Catalá de la Salut, Barcelona, España., Diplomada Universitaria en Enfermería, ABS Sant Andreu de la Barça, Barcelona, España.