The effect of lifestyle modification and glycemic control on the efficiency of sildenafil citrate in patients with erectile dysfunction due to type-2 diabetes mellitus

We evaluated the effect of lifestyle modifications and glycemic control on the efficiency of sildenafil citrate in patients with type-2 diabetes (T2DM) and erectile dysfunction (ED).

Eighty-three men with ED due to T2DM were included in the study.

The Group 1 (n = 41) patients received lifestyle modifications (diet and exercise), and medical treatment for intensive glycemic control. In Group 2 (n = 42), in addition to the intensive glycemic control, the patients were given sildenafil citrate® 100 mg for 2-3 per weeks. The changes in ED were compared between the two groups after three months of treatment.

The mean age was 54 9 ± 9 1 (26-75) years. An increase in the IIEF-5 scores was observed in 23 of 41 patients in Group 1 (44 2%) and 29 of 42 in Group 2 (55 8%). When the changes of the IIEF-5 scores were evaluated, the mean increase was 2 5 in Group 1, and 5 0 in Group 2 (p = 0 012). The mean IIEF changes according to the duration of diabetes were 4 8 in 10 years (p = 0 021).

Glycemic control and lifestyle changes are not solely adequate for a better sexual function in ED due to diabetes, and sildenafil citrate should be used additionally.

The aging male : the official journal of the International Society for the Study of the Aging Male 2015 Aug 06 [Epub ahead of print]

Utku Kirilmaz, Ozer Guzel, Yilmaz Aslan, Melih Balci, Altug Tuncel, Ali Atan

Department of Urology, Ankara Numune Research and Training Hospital , Ankara , Turkey

PubMed