To determine the association between chronic periodontitis and erectile dysfunction adjusting for biochemical markers and other co-morbidities.
A case-control study was conducted on 158 male patients. 80 cases with erectile dysfunction according to the International Index of Erectile Function, and 78 controls. Sociodemographic data were gathered and a periodontal examination was performed. Testosterone, lipid profile, C-reactive protein and glycaemic parameters were assessed. All variables were compared between groups and multivariate logistic regression analyses were performed.
74% of the cases were diagnosed with chronic periodontitis. Number of sites with pocket probing depth 4-6 mm (p=0.05) and number of sites with clinical attachment loss >3 mm (p<0.01) were higher in the cases. Triglycerides (p<0.01), C-reactive protein (p=0.02) and glycosylated haemoglobin (p=0.04) were also higher in the cases. Logistic regression showed that patients with chronic periodontitis were more likely to have erectile dysfunction (OR=2.17; 95%CI (1.06-4.43); p=0.03) independently of other confounders.
Patients with erectile dysfunction showed worse periodontal condition. Chronic periodontitis seems to play a key role as a risk factor in the pathogenesis of erectile dysfunction independently of other morbidities. This article is protected by copyright. All rights reserved.
Journal of clinical periodontology. 2018 May 03 [Epub ahead of print]
Amada Martín, Manuel Bravo, Miguel Arrabal, Antonio Magán-Fernández, Francisco Mesa
Department of Periodontics, School of Dentistry, University of Granada, Granada, Spain., Department of Preventive and Community Dentistry, School of Dentistry, University of Granada, Granada, Spain., Urology Unit, Granada University Hospital Complex, Granada, Spain.