To investigate the correlation of clinical measurements on normal and abnormal fasting blood glucose (FBG) with benign prostatic hyperplasia (BPH).
From September 2016 to January 2018, 771 BPH patients were enrolled for further selection. The eligible patients were divided into normal FBG, impaired fasting glucose (IFG), and high risk of type 2 diabetes mellitus (HR-T2DM) groups. Then, relevant parameters were compared among these three groups using Pearson's correlation coefficient.
Finally including 443 patients with normal FBG, 113 with IFG and 56 with HR-T2DM. Height, weight, body mass index, smoking status, hemoglobin, serum Na+, serum Cl-, and serum Ca2+ were significantly different between normal and abnormal FBG groups. In IFG/HR-T2DM group, obviously connections were demonstrated for weight with prostate volume (PV), for serum Na+, PV, and serum Cl- with total prostate-specific antigen (t-PSA), for FBG with international prostate symptom score (IPSS). In normal FBG group, significant correlations of age, weight, body mass index, hemoglobin, and serum Ca2+ with PV, of age, systolic blood pressure, PV, and serum Cl- with t-PSA; and of FBG, hemoglobin, and serum Na+ with IPSS were also observed.
Our study suggests that FBG level probably plays an important role in BPH.
The aging male : the official journal of the International Society for the Study of the Aging Male. 2019 Feb 10 [Epub ahead of print]
Ming-Juan Zhao, Qiao Huang, Xing-Huan Wang, Xuan-Yi Ren, Ying-Hui Jin, Xian-Tao Zeng
a Center for Evidence-Based and Translational Medicine , Zhongnan Hospital of Wuhan University , Wuhan , China., d Department of Urology , Kaifeng Central Hospital , Kaifeng , China.