To assess interconnection between components of metabolic syndrome with lower urinary tract symptoms and level of androgens 30 young patients with metabolic syndrome were examined. The control group consisted of 32 apparently healthy individuals of comparable age. Revealed a high frequency of increasing the size and volume of the prostate gland, the number of points on the IPSS questionnaire, corresponding to the initial manifestation of hyperplastic prostate diseases on the background of insulin resistance and normal androgen levels raises questions about the search for new pathogenetic links of the metabolic syndrome with the processes of induction of prostate growth.
Endocrine, metabolic & immune disorders drug targets. 2018 Feb 12 [Epub ahead of print]
Svetlana Igorevna Kseneva, Zakhar Aleksandrovich Yurmazov, Maksim Sergeevich Timofeev, Elena Valentinovna Borodulina, Vladimir Vasilievich Udut
Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk. Russian Federation., Cancer Research Institute Tomsk. Russian Federation., Goldberg Research Institute of Pharmacology and Regenerative Medicine Tomsk. Russian Federation.