Benign prostatic hyperplasia (BPH) is very common in aging men and causes lower urinary tract symptoms (LUTS), which decrease health-related quality of life. A number of evidence suggests that other than ageing, modifiable factors, such as increasing prostate volume, obesity, diet, dyslipidemia, hormonal imbalance, hypertension, metabolic syndrome, alcohol, and smoking, also contribute to the development of BPH and/or LUTS. More recently, erectile dysfunction (ED) has been linked to LUTS/BPH as a part of this syndrome, suggesting that patients with BPH or LUTS easily develop ED, and that LUTS/BPH symptoms often coexist with ED. This article focuses on the epidemiology and risk factors of the combined phenotype LUTS/BPH - ED.
The aging male : the official journal of the International Society for the Study of the Aging Male. 2018 Feb 02 [Epub ahead of print]
Aldo E Calogero, Giovanni Burgio, Rosita A Condorelli, Rossella Cannarella, Sandro La Vignera
a Department of Clinical and Experimental Medicine , University of Catania , Catania , Italy.