Hypogonadism is a condition in which the endogenous secretion of testosterone is either insufficient or inadequate to maintain serum testosterone levels within normal range, and may manifest as a variety of signs and symptoms.
Age-related hypogonadism is due to a combination of primary hypogonadism (testicular failure) and secondary hypogonadism (hypothalamic-pituitary axis failure). This review provides insight into the mechanisms resulting in the multifactorial nature of acquired androgen-deficiency, and outlines the current controversy regarding testosterone-replacement therapy in aging males.
Written by:
Golan R, Scovell JM, Ramasamy R. Are you the author?
Department of Urology, New York Presbyterian Hospital, Weill Cornell Medical College, New York, NY, USA.
Reference: Aging Male. 2015 Jun 15:1-4.
doi: 10.3109/13685538.2015.1052392
PubMed Abstract
PMID: 26075536