INTRODUCTION: Decreasing of testosterone level is an important part of a male elderly.
MATERIAL AND METHODS: To describe this phenomenon a PubMed and national databases were searched for 17β-dehydrotestosterone, common testosterone, free testosterone, 17β-estradiol, luteinizing hormone, partial androgen deficiency of aging men.
RESULTS: The reduction in intensity of the processes of tissue renewal of the testicles results in a partial androgen deficiency of aging men. A decrease in the levels of total and free testosterone and an increase in the levels of 5α-dihydrotestosterone, 17β-estradiol, sex hormone binding globulin, LH and FSH, along with a decrease in the amplitude of the rhythm of incretion of LH, FSH and total testosterone will testify to a deficiency of testosterone.
CONCLUSIONS: It is very important to make an individualized selection of the dose of testosterone preparation which enters the blood plasma.
Pechersky A. Are you the author?
Department of Urology, North-Western State Medical University named after I.I. Mechnikov, St. Petersburg, Russia.
Reference: Cent European J Urol. 2014;67(4):397-404.