Hormonal deficiencies in the elderly: Is there a place for a replacement therapy? - Abstract

Biological aging is characterized by a progressive loss of the secretion of various hormones, a phenomenon that leads some physicians to propose an anti-aging hormonal therapy.

It is mandatory to differentiate: 1) the physiological functional loss, which is a natural phenomenon without clear deleterious consequences on health and should not be compensated by the administration of hormones only to restore plasma levels similar to those measured in young people and 2) a pathological defect that deserves a replacement therapy to correct the endocrine deficiency and improve the health status of older individuals. This article considers the deficiencies in insulin, thyroid hormones, growth hormone, dehydroepiandrosterone (DHEA) and testosterone. For each hormone, a benefit/risk ratio of a so-called replacement therapy will be analyzed.

Written by:
Racaru-Honciuc V, Betea D, Scheen AJ.   Are you the author?

Reference: Rev Med Suisse. 2014 Aug 27;10(439):1555-6, 1558-61.

PubMed Abstract
PMID: 25272673

Article in French.

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