Influence of testosterone gel treatment on spermatogenesis in men with hypogonadism - Abstract

The prevalence of androgen deficiency in reproductive-aged men is increasing and needs new approach to long-term hypogonadism treatment that can preserve fertility.

An open non-controlled pilot study included 18 men with eugonadotropic hypogonadism, who received transdermal testosterone gel treatment for 3 months. Sperm analysis was made before treatment and after 3 month of testosterone therapy. Testosterone level was normalized in all patients, but no negative effect was observed on spermatogenesis. Testosterone gel therapy may be a therapy of choice in hypogonadal men of reproductive age but further studies are needed.

Written by:
George M, Yulia T, Svetlana K.   Are you the author?
Andrology and Endocrinology Department, Center for Reproductive Medicine MAMA, Moscow , Russian Federation.

Reference: Gynecol Endocrinol. 2014 Oct;30 Suppl 1:22-4.
doi: 10.3109/09513590.2014.945777

PubMed Abstract
PMID: 25200823 Androgen Deficiency Section