Clinical and Genomic Characterization of Treatment-Emergent Small-Cell Neuroendocrine Prostate Cancer
March 29, 2024
Aggressive Variant Prostate Cancer: Identifying Patients with Specific Molecular Signature
Ana Aparicio, MD
Ana Aparicio discusses her work with aggressive variant prostate cancer and her group’s research using immunohistochemistry results and genomic analysis to identify patients with a specific molecular signature.
Clinical and Genomic Characterization of Treatment-Emergent Small-Cell Neuroendocrine Prostate Cancer
Rahul Aggarwal, MD
Charles Ryan invites Rahul Aggarwal to talk about a paper published in the Journal of Clinical Oncology on treatment-emergent small-cell neuroendocrine prostate cancer, an area not well characterized in the era of modern androgen receptor (AR)-targeting therapy.
Kenneth J. Pienta, MD
Kenneth Pienta joins Charles Ryan at the 26th Annual Prostate Cancer Foundation Scientific Retreat to discuss the biology of prostate cancer, and to share a clinician's perspective of thinking about the biology of this disease.
Justin Drake, MD, BS
Justin Drake discusses the latest and ongoing research associated with the correlation between RET gene expression and neuroendocrine prostate cancer.
Using Circulating Tumor DNA to Detect Neuroendocrine Prostate Cancer Genomic and DNA Methylation Changes
Himisha Beltran, MD
Misha Beltran presented a study where 62 patients across the metastatic disease spectrum were evaluated. The patients had matched metastatic tumor biopsy and plasma samples including serial samples with overall 73 plasma and 116 metastatic tissues obtained. A comprehensive approach was undertaken with CTDNA whole-exome sequencing plus biopsies plus germline DNA analysis performed.