Adrenal Diseases

Primary adrenal lymphoma as a cause of adrenal insufficiency, a report of two cases.

Primary adrenal lymphoma (PAL) is a rare cause of adrenal insufficiency. More than 90% is of B-cell origin. The condition is bilateral in up to 75% of cases, with adrenal insufficiency in two of three patients.

18F-FDOPA PET/CT accurately identifies MEN1-associated pheochromocytoma.

Pheochromocytoma (PHEO) in multiple endocrine neoplasia type 1 (MEN1) is extremely rare. The incidence is reported as less than 2%. We report a case of a 76-year-old male with familial MEN1 who was found to have unilateral PHEO.

Objective response and prolonged disease control of advanced adrenocortical carcinoma with cabozantinib.

Objective response of advanced adrenocortical carcinoma (ACC) to mitotane and cytotoxic chemotherapy regimen is only ~20% and early tumor progression is frequent. Previous clinical trials with oral multi-kinase inhibitors were negative which has been attributed in part to inadvertent drug interaction with mitotane.

Current role of open surgery in adrenal tumors.

The aim of this retrospective evaluation is to assess the current role of open adrenalectomy, in particular in cases of adrenocortical carcinoma (ACC).

From January 2009 to May 2019, 26 open out of 233 adrenalectomies were performed in our Academic Department.

Adrenalectomy for Primary Aldosteronism: Significant Variability in Work-Up Strategies and Low Guideline Adherence in Worldwide Daily Clinical Practice.

Various diagnostic tests are available to establish the primary aldosteronism (PA) diagnosis and to determine the disease laterality. Combined with the controversies in the literature, unawareness of guidelines and technical demands and high costs of some of these diagnostics, this could lead to significant differences in work-up strategies worldwide.

Stereotactic body radiotherapy (SBRT) for adrenal metastases of oligometastatic or oligoprogressive tumor patients.

Local ablative treatment strategies are frequently offered to patients diagnosed with oligometastatic disease. Stereotactic body radiotherapy (SBRT), as ablative treatment option, is well established for lung and liver metastases, whereas for isolated adrenal gland metastases the level of evidence is scarce.

Adrenocortical carcinoma and pulmonary embolism from tumoral extension.

Adrenococortical carcinoma (ACC) is a rare cancer, occurring at the rate of one case in two million person years. Cushing syndrome or a mixed picture of excess androgen and glucocorticoid production are the most common presentations of ACC.

Adrenocortical carcinoma in a young adult male with chronic urticaria: A case report and literature review.

Adrenocortical carcinoma (ACC) is a rare endocrine malignancy, often with an unfavorable prognosis. Radical adrenalectomy is the gold standard of treatment of localized disease.

We report a case of a 23-year-old male patient who presented with persistent left flank pain and urticaria for 3 months.

The clinical utility of 'GRAS' parameters in stage I-III adrenocortical carcinomas: long-term data from a high-volume institution.

Adrenocortical carcinoma (ACC) is a rare cancer with poor survival. We sought to identify prognostic factors and assess its clinical utility in postoperative management of nonmetastatic ACC.

We included 65 patients who underwent adrenalectomy and clinicopathological diagnosed as European Network for the Study of Adrenal Tumors (ENSAT) stage I-III ACC in our center from 2009 to 2017.

Laparoscopic Adrenalectomy for the Treatment of Isolated Large Adrenal Gland Metastases from Malignant Melanoma: A Case Report.

The adrenal gland is a common site for metastatic disease. However, isolated adrenal metastases (AM) are rare. We present a case of a rapidly enlarging adrenal mass with solitary distant metastasis from primary malignant melanoma.