SUFU WM 2015 - Predictors of incomplete bladder emptying requiring CIC following intradetrusor onabotulinum toxin A (BTA) - Session Highlights

SCOTTSDALE, AZ USA (UroToday.com) - Urinary retention requiring intermittent self-catheterization (ISC) following BTA ranges from 6.1% to 6.9%. Although the need for ISC does not appear to affect patient satisfaction, its risk may deter some patients from electing treatment with BTA as the patient must be willing to perform ISC as a condition to BTA injections. Little is known about risk factors for developing incomplete urinary retention post-BTA injection, although certain patient characteristics are thought to be associated. It also is not known if there are baseline factors that can predict urinary retention following BTA injections.

sufuThese authors conducted a retrospective chart review of patients treated with intradetrusor BTA between 2010 and 2014 to determine the incidence of ISC initiation and to identify predictors of incomplete emptying) in patients with OAB with incontinence. In this clinical population, all patients had refractory OAB and were treated with 100U. Patients with neurogenic DO were excluded. Logistic regression models were used for UDS and uroflow parameter as well as patient demographic. ISC was initiated if there was a PVR of 200–350mL, with symptoms, or >350 ml, with or without symptoms.

These authors did not find any predictors of retention in their clinical population (n= 109; mean age 74.8). Seven patients (6.4%) with a mean age of 74.8 required ISC for a mean duration of 9 weeks.

Presented by E. Enemchukwu, N. Talreja, D. Bryck, A. Flores-Aguayo, and V. Nitti at the Society of Urodynamics, Female Pelvic Medicine and Urogenital Reconstruction (SUFU) Winter Meeting - February 24 - 28, 2015 - JW Marriott Camelback Inn Resort & Spa - Scottsdale, AZ USA

Reported by Diane K. Newman, DNP, FAAN, BCB-PMD, medical writer for UroToday.com.