In another arm, zoledronic acid was co-introduced with the Radium-223. The animals were sacrificed at 24 or 96 hours p.i. and the major organs were measured for activity. The results show that all supplement's effect on the biodistribution, although there was no significant difference among the three.
Preclinical in Vitro Nanocarriers/Safety, Regulation
Presented by: Ján Kozempel, PhD, Faculty of Nuclear Sciences and Physical Engineering, Czech Technical University, Prague, Czechia
Written by: William Carithers, Lawrence Berkeley National Laboratory at the 11th International Symposium on Targeted Alpha Therapy (TAT-10) April 1 - April 4, 2019 - Ottawa, ON, Canada