In the second part of the study, two groups of mice were injected with Bi213-DPTA-Nb either with or without 150 mg/kg Gelofusin. Both groups showed good tumor uptake. There is little uptake in normal tissue, but some kidney retention occurred because of excretion through the urine. The kidney retention was reduced by 50% in the Gelofusin arm.
Presented by: Ms. Yana Dekempeneer, Studiecentrum voor Kernenergie (SCK-CEN)
Written by: William Carithers, Lawrence Berkeley National Laboratory at the 11th International Symposium on Targeted Alpha Therapy (TAT-10) April 1 - April 4, 2019 - Ottawa, ON, Canada