SUFU 2019: Caffeine and Other Bladder Irritant Avoidance from Three-Day Voiding Diaries Among Adults with and Without Urgency Incontinence

Miami, FL ( The primary objective of the study was to evaluate the consumption of bladder irritants (caffeine and other fluids) in men and women with and without urge urinary incontinence (UUI). Data was utilized from the 3-day voiding diaries completed by the participants of the Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN).  Only completed bladder diaries were used for data analysis. Researchers defined UUI as subject’s indication of “sometimes” or greater to the question about leaking urine in connection with a sudden need to rush to urinate (LUTS Tool questionnaire).

Total number of 461 diaries was used for analysis (see Figure 1). Women reported UUI more often compared to men (66% vs 34%, p<0.001). According to the presentation, participants who reported UUI and urgency had a higher BMI compared to the participants without UUI and urgency (30 vs 28, p<0.001 for UUI group; 29 vs 28, p=0.042 for the urgency group).
UroToday SUFU2019 Bladder Irritant 1
Figure 1

Overall, participants with UUI had a lower fluid intake compared to the non-UUI group. UUI group was 45% less likely to consume caffeine (OR=0.55, 95 CI 0.32;0.95, p=0.03) (Figure 2). 
UroToday SUFU2019 Bladder Irritant 2
Figure 2

Data analysis shows that men and women who reported urgency on the LUTS Tool Questionnaire were 31% less likely to consume alcohol (OR 0.682, p=0.0675) after adjusting for BMI, age, and intake volume. There was no significant difference in the consumption of caffeine, carbonated and acidic beverages between urgent and non-urgent groups.

This study showed that people with UUI consume a lower amount of fluid and more likely to reduce their caffeine intake than people without UUI.

Presented by: Anne P. Cameron, MD, FPMRS, University of Michigan, Margaret E. Helmuth, Arbor Research Collaborative for Health, Abigail R. Smith, Arbor Research Collaborative for Health H. Henry Lai, Washington University School of Medicine Cindy L. Amundsen, Department of Obstetrics and Gynecology, Duke University,  Ziya Kirkali, National Institute of Diabetes and Digestive and Kidney Diseases, Brenda W. Gillespie, University of Michigan Claire C. Yang, University of Washington
J. Quentin Clemens, and the LURN Study, University of Michigan

Written by: Hanna Stambakio, BS, Clinical Research Coordinator, Division of Urology, University of Pennsylvania, Twitter: @AStambakio at the Society of Urodynamics, Female Pelvic Medicine & Urogenital Reconstruction Winter Meeting, SUFU 2019, February 26 - March 2, 2019, Miami, Florida

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