SIU Congress 2016: Bladder cancer: Frailty as a predictor of complications in older patients undergoing radical cystectomy - Session Highlights


Buenos Aires, Argentina (UroToday.com) Sia Daneshmand, Professor at the University of Southern California, discussed use of frailty as a predictor of complications among elderly patients undergoing radical cystectomy.


Analyzing patients retrospectively (prospectively measured) using grip strength, walking speed, physical activity, shrinking and exhaustion. Comorbidities were assessed via standardized instruments. Shrinking was associated with a greater 30-day complication rate with a similar trend in patients frail grip strength. On multivariate analysis frail grip strength was associated with increased number of complications after controlling for pathologic stage and albumin. These results suggest a cost-effective alternative assessing frailty as well as interventions in these patients needed to decrease complications. At our institution, we use sarcopenia as measured by CT imaging as an assessment of frailty and decreased muscle mass index in order to identify patients who may benefit from aggressive perioperative nutrition counseling and supplementation.

World Urological Oncology Federation Symposium at the SIU Congress 2016 - October 20 - 23, 2016 – Buenos Aires, Argentina

Written By: Stephen B. Williams, M.D., Assistant Professor in Urology, The University of Texas Medical Branch, Galveston, TX. and Ashish Kamat, M.D. Professor, Department of Urology, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX.
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