EAU 2018: 5-year Follow-up of Low Power Holmium Laser Enucleation of the Prostate (HoLEP)

Copenhagen, Denmark (UroToday.com) Benign prostatic hyperplasia remains one of the most common conditions affecting older men with LUTS. Sequelae of BPH include a decrease in urinary flow, and if not treated may ultimately culminate in urinary retention. Fortunately, there are multiple treatment modalities that have been shown to be effective in the management of BPH. These include TURP, holmium laser enucleation of the prostate (HoLEP) and photoselective vaporization of the prostate and many others.

Dr. X. Zou, a clinical urologist from Hospital of Gannan Medical University, Dept. of Urology, Ganzhou, China, presented on a 5-year prospective study that compared the clinical outcomes between low power holmium laser enucleation of the prostate (HoLEP) and transurethral resection of the prostate (TURP) in patients diagnosed with bladder outflow obstruction (BOO) secondary to benign prostatic hyperplasia (BPH).

For this comparison, various post-operative parameters were analyzed in 240 patients who were preoperatively randomized into either HoLEP or TURP groups. Of those parameters, difference in operating time, prostate weight, serum Na+ at 30 minutes post-operation, complications, catheter washing time, indwelling catheter time and postoperative hospital time were statistically significant (p<0.05). Furthermore, the HoLEP group also displayed significantly lower blood loss, serum Na+ changes, hospital times, catheter washing and indwelling times when compared to the TURP group.

In conclusion, both HoLEP and TURP were equally able to relieve lower urinary tract symptoms, however HoLEP exhibited superior long-term efficacy when compared to TURP.

Speaker: Dr. X. Zou, First Affiliated Hospital of Gannan Medical University, Dept. of Urology, Ganzhou, China

Written by: Whitney Zhang, Department of Urology, University of California-Irvine at the 2018 European Association of Urology Meeting EAU18, 16-20 March, 2018 Copenhagen, Denmark