EAU 2018: The Impact of Acute Kidney Injury on Prognosis in Patients With Urological Sepsis

Copenhagen, Denmark (UroToday.com) Acute kidney injury (AKI) is common in patients who have undergone urological procedures. AKI is increasing in incidence and is associated with longer hospitals stays for patients as well as considerable morbidity and mortality. Although common not much is known about the effect of AKI in patients with urological sepsis.

Dr. Fujita and team analyzed a total of 137 patients who were treated for urological sepsis over a 15-month period at their institution. All patients were diagnosed by AKI staging (0-3) and separated into 2 groups: 0-1 AKI and 2-3 AKI. These two groups were compared based on overall survival for 28 days, hospital mortality, ICU admission and hospital stay times.

Of the 137 patients, 97 were 0-1 AKI and 40 were 2-3 AKI. There was a significant difference seen between the two groups for overall survival for 28 days, hospital mortality and ICU admission. All were significantly higher in 2-3 AKI urological sepsis patients when compared with 0-1 AKI urological sepsis patients. There was no significant difference seen in hospital stays between the two groups.

Kidney function plays a crucial role in patients being treated for urological sepsis. Acute kidney injury is common in these patients. This study compared sepsis patients depending on AKI stage and found significantly worse clinical outcome for sepsis patient with 2-3 AKI. The information in this study may serve as an important factor when predicting outcomes in urological sepsis patients with acute kidney injury.

Speaker: S. Celik

Authors: Fujita N., Hatakeyama S., Tobisawa Y., Yoneyama T., Yamamoto H., Imai A., Yoneyama T., Hashimoto Y., Koie T., Yoshikawa K., Ohyama C.

Written by: Renai Yoon, Department of Urology, University of California-Irvine, at the 2018 European Association of Urology Meeting EAU18, 16-20 March, 2018 Copenhagen, Denmark