San Diego, CA USA (UroToday.com) Hospitalization due to infection is a feared complication following prostate biopsy. In order to further understand the risk factors for infection-related hospitalization following prostate biopsy, a pre-biopsy checklist for patients was created.
Risk factors included diabetes, patient/family occupational exposure to healthcare facility, prior antibiotic use within 6 months of biopsy, international travel within 6 months of biopsy, prior biopsy, and immunosuppressant medication. Data was collected from 37 institutions from a prospectively maintained registry for patients undergoing prostate biopsy (MUSIC – the Michigan Urological Surgery Improvement Collaborative) between July 2013 and August 2015.
For a total of 9,396 men who completed the checklist, the infection-related hospitalization rate was 0.70%. 37% of patients who completed the checklist had no risk factors. The most common risk factor among those who were hospitalized was antibiotic use within six months of the biopsy (31.8%), followed by diabetes (27.3%) and then patient/family occupational exposure to healthcare facility (21.2%). The rate of hospitalization was significantly higher for patients with 2 or more risk factors.
Further understanding of the risk factors associated with hospitalization for infection following prostate biopsy is important for patient management, potentially altering the urologist’s counseling and choice of medication. Although this was a univariate analysis, a statistically significant increase in hospitalization rate was noted in patients with two or more comorbidities/risk factors. Further investigation into these risk factors as well as strategies to reduce infection-related complications is warranted.
Presented By: Richard Sarle, MD
Written By: Rahul Dutta, BS; Urology Fellow, Department of Urology, University of California, Irvine at the 2016 AUA Annual Meeting - May 6 - 10, 2016 – San Diego, California, USA