San Diego, CA USA (UroToday.com) Toby Chai presented on State-of-the-Art: Pathophysiology of Neurogenic Detrusor Overactivity. He began by describing some of the goals of treatment of patients with neurogenic detrusor overactivity, which included the overarching pathophysiologic goal of returning storage/emptying reflexes to normal, but also the clinical goals of diminishing sensory urgency, reducing urinary frequency, and decreasing incontinence.
He also discussed new ways to study neurogenic detrusor overactivity that can be explored, including Big Data, genomics, proteomics, metabolomics, transgenic animals, cellular imaging and functional brain imaging.
He also discussed avenues for future research, including studying the urothelium and lamina propria and the impact of the cellular communication and nerve fibers of the lamina propria on neurogenic detrusor overactivity.
Presented By: Toby Chai, MD
Written By: Lindsey Cassini Cox M.D. Clinical Assistant Professor, Female Pelvic Medicine & Reconstructive Surgery, MUSC Health, Medical University of South Carolina, at the 2016 AUA Annual Meeting - May 6 - 10, 2016 – San Diego, California, USA