ICS 2018: Prevalence and Risk Factors of Nocturnal Polyuria in Female Overactive Bladder Syndrome

Philadelphia, PA (UroToday.com) Nocturnal polyuria (NP) is a common complain in women with overactive bladder (OAB), but its’ true prevalence is unknown. This study attempted to assess risk factors related to NP and investigate if additional treatment options are needed in patients with OAB in female cohort in Taiwan in July 2008 - January 2018.

Dr. Hsiao and colleagues analyzed data on 1,071 women who visited a healthcare clinic for the complaint of overactive bladder. Researchers have divided eligible participants into 2 groups based on the completion of a 3-day voiding diary. Women who reported at least one episode of urge urinary incontinence and no stress urinary incontinence were classified as OAB-wet. All other female patients were assigned to the OAB-dry group.

Examining nighttime voided volume over 24-hour voided volume assessed presence of nocturnal polyuria. If the proportion of nocturic volume was greater than 33% for females ages 65 and older and greater than 20% for female less than 65 years of age, subjects were defined as having nocturnal polyuria.

Study showed that NP was present in 35.9% of women under 65 and 17.4% of women ≥65 years of age (Figure 1)

Figure 1

Risk factors related to nocturnal polyuria included participant’s age, parity status, presence of daytime urge urinary incontinence episodes, urinary frequency, and nighttime voiding (Figure 2).

Figure 2

According to the presenter, nocturnal polyuria is present in a number of OAB patients, particularly in women who reported 5 or more nighttime voids over 3 consecutive days. It would be beneficial to complement OAB treatment with additional options to manage symptoms of NP.

Presented by Sheng-Mou Hsiao, MD, Department of Obstetrics & Gynecology, Far Eastern Memorial Hospital, New Taipei, Taiwan.

Coauthors: Chang T, Chen C, Wu W, Lin H, Department of Obstetrics & Gynecology, National Taiwan University Hospital, Taipei, Taiwan

Written by: Hanna Stambakio, BS, Clinical Research Coordinator, Division of Urology, University of Pennsylvania, Twitter: @PennUrology at the 2018 ICS International Continence Society Meeting - August 28 - 31, 2018 – Philadelphia, PA USA