EAU 2018

EAU 2018: The Importance of the Size of Nodal Metastases in Predicting Recurrence of Node-positive Prostate Cancer Patients Treated with Radical Prostatectomy and Extended Pelvic Lymph Node Dissection: Implications For Post-operative Treatment Tailoring

Copenhagen, Denmark (UroToday.com) Patients found to have nodal involvement at the time of radical prostatectomy present a treatment quandary given the different prognostic pathways some of these patients may follow. It is then not surprising that the level one data reported by ECOG 3886 is seldomly followed, which advocated for early hormonal treatment in patients with node positive disease.

EAU 2018: Comprehensive Genomic Profiling of Neuroendocrine Bladder Cancer Pinpoints Molecular Origin and Potential Therapeutics

Copenhagen, Denmark (UroToday.com) Neuroendocrine bladder cancer (NEBC) is rare but clinically aggressive. It encompasses several different subtypes, such as small cell, large cell, and paragangliomas. Because of its rarity, little is known about its genetic underpinnings, making it difficult to formulate effective strategies for treatment.

EAU 2018: Prospective validation of a diagnostic urine test for bladder cancer: The HEMAturia study

Copenhagen, Denmark (UroToday.com) Kim E.M. van Kessel presented on an extremely exciting validation study of a urine-based diagnostic assay for bladder cancer: The HEMAturia study. The authors have previously published their findings on this test using a discovery cohort and retrospective validation cohort, reporting >90% sensitivity and 83-85% specificity.

EAU 2018: Monitoring: Can we skip biopsies?

Copenhagen, Denmark (UroToday.com) Dr. Antti Rannikko summarized this morning’s debate on the utility of MRI-targeted fusion biopsies for men on active surveillance (AS).

EAU 2018: Which Role Does the Intraoperative Ultrasonography Have in a Nephron-Sparing Surgery Setting?

Copenhagen, Denmark (UroToday.com) Preservation of renal function is the main feature of nephron-sparing surgery. In the setting of evaluation of renal function prior and after partial nephrectomy (PN), renal scintigraphy (RS) and volumetric assessment (VA) have gained popularity due to the more precise estimation of effective renal function allowed before and after PN. At the time of PN, the use of intraoperative ultrasonography (US) is a worldwide used procedure, but no definitive answers have been published, on whether it results in any advantage.

EAU 2018: Comprehensive Comparison of CSA, RENAL, PADUA, and C-Index in Predicting Functional Change after Partial Nephrectomy in Small Renal Mass

Copenhagen, Denmark (UroToday.com) This study evaluated the renal cortical volume (RCV) change after nephron sparing surgery and the predictive value of nephrometry score in RCV preservation after partial nephrectomy (PN).

EAU 2018: Point-counterpoint session Selection for active surveillance: Only Magnetic Resonance Imaging (MRI)-targeted lesions are relevant-Con

Copenhagen, Denmark (UroToday.com) Dr. Arsov presented the counterpoint to Dr. Moore regarding the appropriateness of relying on MRI-targeted lesions for men being selected for active surveillance (AS). He started by posing a question: Should we really let all men with negative MRIs get away without a biopsy? Indeed, evidence suggests that we should exercise caution; a negative MRI cannot completely rule out high grade disease.