AUA 2018

AUA 2018: Oncologic Outcomes of Simple Enucleation Partial Nephrectomy in Sporadic Type 2 Papillary Renal Cell Carcinoma

San Francisco, CA (UroToday.com) Papillary type 2 renal cell carcinoma (RCC) has been associated with poor prognosis and increased risk of local recurrence according to studies in patients with Hereditary Leiomyomatosis and RCC. The current recommendation for patients found to have papillary type 2 features on biopsy is for radical nephrectomy or partial nephrectomy with a wide margin. The authors aimed to assess the margin rate along with fossa recurrence rate of patients with sporadic type 2 papillary RCC who underwent simple enucleation partial nephrectomy as compared to those with clear cell RCC. 

AUA 2018: The Prevalence and Biopsychosocial Predictors of Suicidality in Men with Prostate Cancer

San Francisco, CA (UroToday.com) Prostate cancer (PCa) is associated with a high rate of depression, more than that reported for the general population. There is a positive association between PCa diagnosis and suicide. The first aim of this study was to establish a point prevalence for suicidality among patients diagnosed with PCa. The second aim was to evaluate what biopsychosocial variables best predict greater risk of suicidality in men with PCa. 

AUA 2018: Outcomes of a Phase III Randomized Controlled Trial Comparing Preventive versus Delayed Ligation of Dorsal Vascular Complex During Robot-Assisted Radical Prostatectomy

San Francisco, CA (UroToday.com) Since the anatomic approach to radical prostatectomy was first described, there have been many attempts to improve the technique. Such innovation has been particularly notable since the widespread adoption of robotic assisted radical prostatectomy. Modifications including the Rocco stitch and Retzius sparing have been undertaken in an attempt to improve clinical outcomes. In a moderated poster presented at the American Urologic Association Annual Meeting, Dr Palumbo and colleagues from Brescia, Italy report on their phase III randomized controlled trial comparing preventative ligation of the dorsal venous complex (DVC) during robotic assisted radical prostatectomy to delayed ligation, following its transection. 

AUA 2018: Assessing the 20-Year Outcomes of Lymph Node Positive Prostate Cancer Patients: A Plea For Lifelong Follow-Up

San Francisco, CA (UroToday.com) Little data are available on oncological outcomes of lymph node metastatic (LNM) prostate cancer (PCa) patients at very long follow-up and on predictors of cancer specific mortality (CSM) in this setting. The authors evaluated the long-term patterns of clinical recurrence (CR) and CSM in a large database of surgically treated LNM PCa patients with at least 20 years of follow-up. 

AUA 2018: Is Fatal Family History in Prostate Cancer a Predictor of Radical Prostatectomy Outcomes?

San Francisco, CA (UroToday.com) It is well known that a family history of prostate cancer, particularly of advanced or fatal disease, increases a man’s chance of being diagnosed with prostate cancer. In this single center study from Munich, Germany which was presented as a moderated poster at the American Urologic Association Annual Meeting, Dr. Herkommer and colleagues assessed the association between a first-degree family history of fatal prostate cancer and outcomes following radical prostatectomy for men diagnosed with prostate cancer. 

AUA 2018: Association Between Environmental Quality and Prostate Cancer Stage at Diagnosis

San Francisco, CA (UroToday.com) Prostate cancer (PC) is reportedly up to 57% heritable, with the remainder attributed to exposures such as diet, medications, or environment. There are limited data regarding environmental exposures and PC aggressiveness, which was the focus of this study.  Using the Surveillance, Epidemiology, and End Results (SEER) database the authors identified PC cases reported between 2010 and 2014.

AUA 2018: Oncological Outcomes of Salvage Radical Prostatectomy in a Contemporary, Multicentre Series of 395 Cases

San Francisco, CA (UroToday.com) While radical prostatectomy is the most commonly utilized treatment for clinically localized prostate cancer in the United States, many patients undergo other treatments including radiotherapy (whether external beam or brachytherapy), cryotherapy, high-intensity focused ultrasound (HIFU), and others. When patients who have undergone these treatments experience biochemical recurrence, management options are not well described. In a moderated poster presented at the American Urologic Association Annual Meeting, Dr. Gontero and colleagues report on a large, multi-institutional cohort from 18 tertiary care centers describing the outcomes of salvage radical prostatectomy in this setting. The authors present data relating to pre-operative, intra-operative, and post-operative factors including functional recovery following surgery.