EAU 2018

EAU 2018: The Impact of Time from Diagnosis to Primary Radical Prostatectomy on Prostate Cancer-Specific Mortality

Copenhagen, Denmark (UroToday.com) Norway has a high incidence of prostate cancer (PCa). In 2016 approximately 5,100 Norwegian men were diagnosed with PCa. About 90% of them had local disease without distant metastases, and most of these patients were candidates for curative treatment, with a life expectancy of 10 years or more. To eliminate unnecessary delay in diagnosis and treatment, the Norwegian health authorities introduced in 2015 a fast-track system stating that patients eligible for primary radical prostatectomy (RP) should undergo surgery within 32 days of decision-making (“RP-interval”), irrespective of the risk group allocation. 

EAU 2018: Prostate Radio-frequency Ablation Focal Treatment - ProRAFT

Copenhagen, Denmark (UroToday.com) Radiofrequency ablation (RFA) using a bipolar coil design (Encage® device) which acts as a Faraday cage offers the versatility needed to perform focal treatment of localised prostate cancer, whilst sparing critical anatomical and functional structures. In this study the authors report final outcomes of an ethics approved prospective development study, investigating focal Encage® ablation (NCT02294903). The primary objective was to determine the ablative efficacy 6 months after bipolar RFA against histology. The secondary objectives included the assessment of genito-urinary toxicity.

EAU 2018: Bi-parametric Prebiopsy MRI in Men with Clinical Suspicion of Prostate Cancer: Prospective Multi-center Validation Trial

Dr. Syvanen and colleagues from Finland presented results of their prospective multi-center validation trial of bi-parametric pre-biopsy MRI in men with clinical suspicion of prostate cancer at today’s EAU 2018 annual meeting. Over the past decade, MRI is widely used in the diagnostics and treatment planning of prostate cancer, but its role in a pre-biopsy setting is still controversial. The aim of the current study was to validate previous single center bi-parametric pre-biopsy MRI results in a prospective multi-centre trial.

EAU 2018: Prostate Cancer: Immediate and Late Complications - Laparoscopic

Copenhagen, Denmark (UroToday.com) Intraoperative complications in laparoscopic radical prostatectomy (LRP) has been reported to occur in 1.6% +/-1.9 of cases, while perioperative complications occur in – 11.1%+/- 9.6% of cases. Complications of LRP can occur due to the learning curve, patient positioning, approach, bleeding, hemorrhage and CO2 embolism, anastomosis, and pelvic lymph node dissection (PLND).

EAU 2018: Prostate Cancer: Immediate and Late Complications - Robotic

Copenhagen, Denmark (UroToday.com) Dr. Evans gave an overview of possible complications in robotic assisted laparoscopic radical prostatectomy (RALRP). He began discussing the complications of patient positioning. The weight of the patient’s leg should be transmitted through the heel and foot. There should be minimal pressure on the lateral aspect of the calves and thighs. The hips should be extended to minimize the risk of femoral nerve injury. It is important to secure the patient well prior to draping. Use of high density padding with a high coefficient of friction is recommended.

EAU 2018: Prostate Cancer: Immediate and Late Complications - Open

Copenhagen, Denmark (UroToday.com) There are plenty of potential complications in open radical prostatectomy (ORP). These include intraoperative, postoperative, and late complications.

EAU 2018: Is Focal Therapy for Prostate Cancer an Attractive Option?

Copenhagen, Denmark (UroToday.com) Focal therapy (FT) for the treatment of localized prostate cancer (PCa) has encouraging medium-term oncological and functional outcomes. Concerns exist about multi-focality, treatment of low-risk cancer that is better served with active surveillance, failure rates, and lack of long-term data. The technique is currently embedded in a few academic institutions with international guidelines limiting its use to clinical trials only. The general urological community’s opinion on FT has never been assessed. Therefore, the authors investigated the current opinion and accessibility of FT in the treatment of PCa in the European urological community.