AUA 2018: In vivo Assessment of a Biodegradable Ureteral Stent Based on Natural Origin Polymers
San Francisco, CA USA (UroToday.com) Alexandre Barros,MD, a PhD post doctorate of Biomaterials, Biodegradables, and Biomimetics of the University of Minho at Braga, Portugal, presented data on the efficacy of a novel hydrogel based biodegradable ureteral stent (BUS) in porcine models compared to the conventional commercial ureteral stent. As an introduction, Dr. Barros stated there has been a prevalence of injuries due to ureteral stents. Because of this, the objective of the study was to evaluate if the biodegradable stent would produce similar ureteral stent effects found with the conventional commercial stent for the ultimate goal of avoiding ureteral injury.
AUA 2018: Radical Versus Partial Nephrectomy for cT1 Renal Cell Carcinoma: A Propensity-Score Based Analysis
San Francisco, CA USA (UroToday.com) Previous observational studies suggest reduced chronic kidney disease risk as well as all-cause mortality in using partial nephrectomy (PN) with respect to radical nephrectomy (RN). However, the only randomized trial comparing PN and RN reported no significant benefit to PN.
AUA 2018: Prospective Validation of a Diagnostic Urine Test For Bladder Cancer: The HEMAturia Study
San Francisco, CA (UroToday.com) Kim van Kessel, MD, presented a validation study of a urine-based diagnostic assay for bladder cancer: The HEMAturia study. The authors have previously published their findings on this test using a discovery cohort and retrospective validation cohort, reporting >90% sensitivity and 83-85% specificity.1,2 However, as those were both case enriched, they are moving to a prospective cohort.
AUA 2018: Postoperative Outcomes of Elderly Patients Undergoing Partial Nephrectomy: A Multicentric-Study of the French Research Network On Kidney Cancer UroCCR
San Francisco, CA USA (UroToday.com) Dr. Sophie, from the University Hospital of Bordeaux presented on partial nephrectomy (PN) in the elderly population. She stressed the importance of preserving renal function as it is an independent predictor of cardiovascular function. Since there is limited data on the feasibility and morbidity of PN for patients over the age of 75 years old, Dr. Sophie sought to shed light on this issue by analyzing the clinical outcomes in this population group.
AUA 2018: Tumor Enucleation: Functional Comparison with Standard Partial Nephrectomy
San Francisco, CA USA (UroToday.com) Suk-Ouichai, from the Glickman Urological and Kidney Institute, Cleveland Clinic presented her research on two nephron-sparing techniques used to treat renal cancer, conventional partial nephrectomy (PN) and tumor enucleation (TE) (Figure 1). TE is like PN but it spares more of the normal parenchymal tissue by dissecting along the avascular pseudocapsule. Therefore, it is thought that TE better preserves renal function compared to PN, however this remains up for debate. Her team sought to shed some light on this issue by analyzing and comparing the functional outcomes of TE and PN.
AUA 2018: Pure Laparoscopic Versus Robot-Assisted Partial Nephrectomy for Ct1b Renal Tumors: A Single Tertiary Center Experience
San Francisco, CA USA (UroToday.com) Dr. Bertolo, from the University of Turin focused on the surgical management of renal cancer with two different partial nephrectomy techniques, laparoscopic partial nephrectomy (LPN) and robotic-assisted partial nephrectomy (RAPN). He suggested that recent literature has shown a superiority in robotic versus laparoscopic surgery, however debates arise around challenging cases.
AUA 2018: Renal Function Variability Can Identify Subclinical Kidney Disease Before Nephrectomy
San Francisco, CA USA (UroToday.com) Andrew Sun, MD and his team at Stanford University sought to determine the relationship between the variability in preoperative kidney function and the onset of chronic kidney disease (CKD) and survival rate after partial and radical nephrectomies. As past studies have shown, variability within kidney function has shown to be correlated with more detrimental renal outcomes for patients with CKD. This study further observed the relationship between preoperative variability and overall survival following partial and radical nephrectomies.