EAU 2018

EAU 2018: Hormone-Naive Prostate Cancer

Copenhagen, Denmark (UroToday.com)  Dr. Joniau gave an overview of hormone-naïve prostate cancer (HNPC). Approximately 5% of the screened population present with de novo metastatic prostate cancer. This represents 1/3 of the prostate cancer (PC) death in the USA each year. The remaining 2/3 of patients relapse after prior localized therapy. They undergo rapid progression to metastasis, with transformation of HSPC to castrate resistant prostate cancer (CRPC), and then to death.  The median time from radical prostatectomy to PSA failure is 24 months (12-44). The median time from PSA failure to metastasis is 32 months (2-129), and finally the median time from metastasis to PC specific mortality is 82 months (7-181). Overall, from PC relapse to PC specific death the median time is 132 months (12-204).

EAU 2018: Highlights from ASCO-GU 2018

Copenhagen, Denmark (UroToday.com)  Dr. Nguyen gave a talk summarizing the recent GU-ASCO 2018 meeting which took place in San-Francisco, USA, earlier this year.

EAU 2018: Castration Resistant Prostate Cancer

Copenhagen, Denmark (UroToday.com)  Dr. Evans gave an overview of the hottest and latest news in the medical treatment of castrate resistant prostate cancer (CRPC).  In metastatic CPRC (MCRPC), plasma circulating tumor DNA (ctDNA) has emerged as a tool to sample the tumor genome.  Up until recently, no systematic comparisons of matched liquid and solid biopsies were performed to enable ctDNA profiling to replace direct tissue sampling.

EAU 2018: Urothelial Cancer – A Year in Highlights

Copenhagen, Denmark (UroToday.com)  Dr. Powles gave an overview of the recent highlights and advances in the treatment of urothelial cancer. Immune checkpoint inhibitors (ICI) are the biggest advancement in urothelial cancer and the licensed ICI in metastatic urothelial cancer (MUC) are shown in figure 1.

EAU 2018: Clinicopathologic Factors Linked to Intravesical Recurrence after Radical Nephroureterectomy to Treat Upper Tract Urothelial Carcinoma

Copenhagen, Denmark (UroToday.com)  Dr. Seisen proided a talk which focused on the clinicopathology factors linked to intravesical recurrence (IVR) following radical nephroureterectomy (RNU) to treat upper tract urothelial carcinoma. His talk was primarily based on the recent systematic review that he spearheaded (Seisen et al, European Urology, 2014). This has since been translated into the guidelines for the EAU.

EAU 2018: Can we Rely on Urinary Markers?

Copenhagen, Denmark (UroToday.com)  Dr. Shariat was tasked with addressing the role of urinary markers for UTUC. The short answer is … no. However, there is a lot of potential for urinary markers, and he provided a summary of the current landscape.

EAU 2018: Instillations in The Upper Tract: Which Technique?

Copenhagen, Denmark (UroToday.com) Dr. Seiler presented a summary of upper tract instillations and a discussion of the best method to utilize.