Clinical Trials

440 results for Prostate Cancer


A Phase III Randomized Study of Hypofractionated Image-guided Volumetric Modulated Arc Radiotherapy (IG-VMAT) Versus Conventionally Fractionated IG-VMAT in Patients With Localized Prostate Cancer

  • Condition: Prostate Cancer
  • Intervention: Radiation: hypofraction, Radiation: convention
  • Study ID: NCT02934685
View Trial

RAD 1203: Pilot Trial Evaluating Stereotactic Body Radiotherapy With Integrated Boost for Clinically Localized Prostate Cancer

  • Condition: Prostate Cancer, Prostate Adenocarcinoma, Radiation Toxicity, Sexual Dysfunction
  • Intervention: Radiation: Stereotactic Body Radiation Therapy with Integrated Boost
  • Study ID: NCT01856855
View Trial

Phase 2 Study of Enzalutamide and GnRH Agonist Before, During and After Radiation Therapy in Treatment of Patients With High-risk Localized Prostate Cancer

  • Condition: Prostate Cancer
  • Intervention: Drug: Enzalutamide, Drug: Leuprolide acetate, Radiation: radiation
  • Study ID: NCT02064582
View Trial

Magnetic Resonance Guided Focal Stereotactic Body Radiation Therapy for Localized Prostate Cancer

  • Condition: Adenocarcinoma of the Prostate, Recurrent Prostate Cancer, Stage I Prostate Cancer, Stage IIA Prostate Cancer, Stage IIB Prostate Cancer
  • Intervention: Radiation: stereotactic radiosurgery, Procedure: magnetic resonance imaging, Other: quality-of-life assessment, Procedure: Serum Prostate Antigen Test, Procedure: Digital Rectal Exam, Behavioral: Expanded Prostate Cancer Index Composite
  • Study ID: NCT02163317
View Trial

A Randomized Controlled Trial of ProstAtak® as Adjuvant to Up-front Radiation Therapy For Localized Prostate Cancer

  • Condition: Prostate Cancer
  • Intervention: Biological: ProstAtak®(AdV-tk) + valacyclovir, Biological: Placebo + valacyclovir
  • Study ID: NCT01436968
View Trial

Randomized Placebo-Controlled, Double-Blind Study of Cholecalciferol Replacement in Patients on Expectant Management for Localized Prostate Cancer

  • Condition: Prostate Adenocarcinoma
  • Intervention: Dietary Supplement: Cholecalciferol, Other: Laboratory Biomarker Analysis, Other: Patient Observation, Drug: Placebo Administration, Other: Quality-of-Life Assessment, Other: Questionnaire Administration
  • Study ID: NCT00887432
View Trial

A Randomized Phase III, Factorial Design, of Cabazitaxel and Pelvic Radiotherapy in Patients With Localized Prostate Cancer and High-risk Features of Relapse

  • Condition: Adenocarcinoma of Prostate, Progression of Prostate Cancer
  • Intervention: Drug: Cabazitaxel, Radiation: Pelvic radiotherapy, Radiation: prostate radiotherapy
  • Study ID: NCT01952223
View Trial

A Phase IIA Exploratory, Randomized, Placebo-Controlled Trial of Pomegranate Fruit Extract/POMx™ in Subjects With Clinically Localized Prostate Cancer Undergoing Active Surveillance

  • Condition: Stage I Prostate Cancer, Stage IIA Prostate Cancer, Stage IIB Prostate Cancer
  • Intervention: Other: Laboratory Biomarker Analysis, Other: Pharmacological Study, Other: Placebo, Drug: Pomegranate-Extract Pill
  • Study ID: NCT02095145
View Trial

Hypofractionated Intensity Modulated and Image Guided Radiotherapy for Localized Prostate Cancer: a Prospective Cohort.

  • Condition: Prostatic Neoplasms
  • Intervention: Radiation: HypoIGRT
  • Study ID: NCT02651896
View Trial

Pre-Operative Gleason Score and PSA and Clinical Stage in Predicting the Risk of Failure in Patients Undergoing Radiation Therapy for Localized Prostate Cancer

  • Condition: Prostate Cancer, Radiation Toxicity
  • Intervention: Other: medical chart review, Other: questionnaire administration, Procedure: quality-of-life assessment, Radiation: brachytherapy, Radiation: radiation therapy
  • Study ID: NCT00769223
View Trial

A Pharmacodynamic Pre-surgical Study of Hedgehog Pathway Inhibition With LDE225 in Men With High-risk Localized Prostate Cancer.

  • Condition: Prostate Cancer
  • Intervention: Drug: LDE225
  • Study ID: NCT02111187
View Trial

Prospective Evaluation of CyberKnife® as Monotherapy or Boost Stereotactic Body Radiotherapy for Intermediate or High Risk Localized Prostate Cancer

  • Condition: Prostate Adenocarcinoma
  • Intervention: Radiation: CyberKnife, Other: Androgen Deprivation Therapy (ADT), Radiation: Intensity Modulated radiation therapy (IMRT)
  • Study ID: NCT01985828
View Trial

A Phase 1 Study of Allogeneic Human Bone Marrow Derived Mesenchymal Stem Cells in Localized Prostate Cancer

  • Condition: Prostate Cancer
  • Intervention: Biological: Allogeneic Human Mesenchymal Stem Cells
  • Study ID: NCT01983709
View Trial

Intimacy-Enhancing Couples' Intervention for Localized Prostate Cancer

  • Condition: Prostate Cancer, Sexual Dysfunction and Infertility, Sexuality
  • Intervention: Other: communication intervention, Other: counseling intervention, Other: nutrition intervention, Other: questionnaire administration
  • Study ID: NCT01982058
View Trial

Hypo-fractionated Stereotactic Body Radiotherapy for Localized Prostate Cancer

  • Condition: Prostate Cancer
  • Study ID: NCT01059513
View Trial

A Randomized Study of Enzalutamide in Patients With Localized Prostate Cancer Undergoing Active Surveillance (ENACT)

  • Condition: Prostate Cancer
  • Intervention: Drug: Enzalutamide, Other: Active Surveillance
  • Study ID: NCT02799745
View Trial

Circulating Tumor Cell Analysis in Patients With Localized Prostate Cancer Undergoing Prostatectomy

  • Condition: Prostate Cancer
  • Study ID: NCT01961713
View Trial

Evaluation of the TULSA-PRO MRI-guided Transurethral Ultrasound Prostate Ablation Device in Patients With Localized Prostate Cancer

  • Condition: Prostate Cancer
  • Intervention: Device: MRI-guided Transurethral Ultrasound Ablation
  • Study ID: NCT02766543
View Trial

A Phase II Randomized Trial Evaluating Acute and Late Toxicity of High-Dose Rate Brachytherapy and Low-Dose Rate Brachytherapy as Monotherapy in Localized Prostate Cancer

  • Condition: Prostate Cancer
  • Intervention: Radiation: Permanent Iodine-125 seed implant, Radiation: High-Dose-rate Prostate Brachytherapy
  • Study ID: NCT02628041
View Trial

Prostate Cancer E-Health-Tutorial (PROCET): Multicenter, One-armed Intervention Study to Evaluate an Online Tutorial for Patients With Localized Prostate Cancer

  • Condition: Prostate Cancer
  • Intervention: Other: Online tutorial
  • Study ID: NCT02503748
View Trial

A Phase I-II Dose Escalation Study of Stereotactic Body Radiation Therapy in Patients With Localized Prostate Cancer

  • Condition: Prostate Adenocarcinoma
  • Intervention: Radiation: Stereotactic Body Radiation Therapy (SBRT)
  • Study ID: NCT02254746
View Trial

Phase II Randomized, Placebo-Controlled Trial of PROSTVAC (PSA-TRICOM) in Patients With Clinically Localized Prostate Cancer Undergoing Active Surveillance

  • Condition: Stage I Prostate Adenocarcinoma, Stage II Prostate Adenocarcinoma
  • Intervention: Other: Laboratory Biomarker Analysis, Other: Placebo, Biological: Rilimogene Galvacirepvec
  • Study ID: NCT02326805
View Trial

Tumor Targeted Radiotherapy for Patients With Localized Prostate Cancer

  • Condition: Prostate Cancer
  • Intervention: Radiation: Volumetric Modulated Arc Therapy (VMAT) and High-Dose Rate (HDR) Radiotherapy, Other: No Active Treatment - completed Prior Radiation
  • Study ID: NCT01802242
View Trial

A Pilot Study of Magnetic Resonance (MR) Imaging With Hyperpolarized Pyruvate (13C) to Detect High Grade Localized Prostate Cancer

  • Condition: Prostate Cancer
  • Intervention: Drug: Pyruvate (13C)
  • Study ID: NCT02526368
View Trial

Effect of Different Exercise Regimens on Intratumoral Natural Killer (NK) Cell Variability in Men With Localized Prostate Cancer Undergoing Radical Prostatectomy - a Randomized Controlled Pilot Study

  • Condition: Prostate Cancer
  • Intervention: Behavioral: High Intensity Interval Training, Behavioral: Moderate-Intensity Aerobic and Resistance Training, Behavioral: Usual Care Observational Control
  • Study ID: NCT02954783
View Trial

The UCLA ASCAP Project is an Observational, Longitudinal, and Open-ended Study Aimed at Establishing a Structured Program of Non-interventional Follow-up for Localized Prostate Cancer.

  • Condition: Prostate Cancer
  • Intervention: Other: Active surveillance
  • Study ID: NCT00949819
View Trial

A Prospective Single-Arm Phase I/II Study Using 11C-Choline PET Scans for Dose Escalated Hypofractionated Image Guided Inversely Planned Intensity Modulated External Beam Radiotherapy With Boost to PET Defined Dominant Intraprostatic Lesions and as a Pred

  • Condition: Prostatic Neoplasms
  • Intervention: Radiation: 11C-Choline
  • Study ID: NCT02004418
View Trial

Phase II Study of Feasibility of Focal Therapy for Prostate Cancer of Good Prognosis With Permanent I125 Localized Implant.

  • Condition: Localized Prostate Cancer
  • Intervention: Radiation: Focal brachytherapy
  • Study ID: NCT01902680
View Trial

Phase II Trial of Hypofractionated Proton Beam Therapy in Men With Localized Prostate Adenocarcinoma

  • Condition: Prostate Cancer
  • Intervention: Radiation: Proton Beam Therapy, Behavioral: Questionnaire
  • Study ID: NCT01950351
View Trial

Comparison of High-dose- Versus Low-dose-rate Brachytherapy as Monotherapy in the Treatment of Early, Organ Confined Prostate Cancer.

  • Condition: Adenocarcinoma of Prostate
  • Intervention: Radiation: LDR Brachytherapy, Radiation: HDR Brachytherapy
  • Study ID: NCT02258087
View Trial

Prospective Evaluation of CyberKnife Stereotactic Body Radiotherapy for Localized Prostate Cancer: Risk Stratified Monotherapy Versus Boost

  • Condition: Prostate Cancer
  • Intervention: Radiation: Stereotactic Ablative Body Radiotherapy as Monotherapy, Radiation: Stereotactic Ablative Body Radiotherapy as a Boost
  • Study ID: NCT02016248
View Trial

An Open Label, Randomized Phase 2 Trial of Prostvac and Ipilimumab as Monotherapy or in Combination for Men With Localized Prostate Cancer Undergoing Radical Prostatectomy

  • Condition: Prostatic Neoplasms
  • Intervention: Biological: PROSTVAC V/F, Drug: Ipilimumab
  • Study ID: NCT02506114
View Trial

Perioperative Pelvic Floor Muscle Training May Improve Recovery of Continence in Men With Localized Prostate Cancer Undergoing Robot-Assisted Radical Prostatectomy

  • Condition: Prostate Cancer, Urinary Incontinence, Pelvic Floor Physical Therapy
  • Intervention: Behavioral: Pelvic Floor Muscle Physical Therapy, Behavioral: Control Group
  • Study ID: NCT02558946
View Trial

Study of Non-Invasive Viberect® Penile Vibratory Stimulation Regimen to Enhance Recovery of Erectile Function/Rigidity and Urinary Control/Continence After Nerve Sparing Radical Prostatectomy (RP) for Clinically Localized Prostate Cancer.

  • Condition: Erectile Dysfunction Following Radical Prostatectomy, Urinary Incontinence of Non-organic Origin
  • Intervention: Device: Viberect device
  • Study ID: NCT01718704
View Trial

Whole-Pelvic Radiotherapy With a Stereotactic Body Radiotherapy Boost and Long-Term Androgen Deprivation for Unfavorable-Intermediate and High Risk Localized Adenocarcinoma of the Prostate.

  • Condition: Adenocarcinoma of the Prostate
  • Intervention: Radiation: Stereotactic Radiosurgical Boost3, Drug: Casodex, Drug: Leuprolide
  • Study ID: NCT02064036
View Trial

Focal Prostate Radio-Frequency Ablation for the Treatment of Prostate Cancer

  • Condition: Prostate Cancer
  • Intervention: Procedure: Radio-Frequency Ablation (RFA)
  • Study ID: NCT02328807
View Trial

An Open Registry to Measure the Impact of Adding Genomic Testing (Prolaris®) on the Treatment Decision Following Biopsy in Newly Diagnosed Prostate Cancer Patients at Intermountain Hospitals

  • Condition: Prostate Cancer
  • Intervention: Behavioral: Registry
  • Study ID: NCT02454595
View Trial

Retrospective Analysis of Quality of Life After Permanent Interstitial Iodine Seed Brachytherapy for Prostate Cancer

  • Condition: Neoplasms, Prostate
  • Intervention: Other: No intervention in this retrospective study
  • Study ID: NCT02652000
View Trial

Early Changes in Multiparametric MRI in Response to Neoadjuvant Androgen Deprivation and External Beam Radiation Therapy for Prostate Cancer

  • Condition: Prostate Cancer
  • Intervention: Device: MRI, Other: PSA Blood Test
  • Study ID: NCT01959542
View Trial

Patient Over 75 Years With Prostate Cancer: Geriatric Determinants of General Repercussion of Radiotherapy With Curative Intent

  • Condition: Prostate Cancer
  • Intervention: Other: geriatric assessment and quality of life, Radiation: Radiotherapy
  • Study ID: NCT02876237
View Trial

Prospective Phase III Randomized Trial of Prostate Only or Whole Pelvic RadioTherapy in High Risk Prostate Cancer (POP-RT) Trial

  • Condition: Prostate Cancer
  • Intervention: Radiation: IGRT
  • Study ID: NCT02302105
View Trial

A Pilot Study to Evaluate the Reproducibility of Magnetic Resonance (MR) Imaging With Hyperpolarized Pyruvate (13C) and Its Ability to Reflect Treatment Effects in Patients With Prostate Cancer

  • Condition: Prostate Cancer
  • Intervention: Drug: Pyruvate
  • Study ID: NCT02450201
View Trial

A Randomized Clinical Trial Comparing the Efficacy of MRI Versus PSA for Prostate Cancer Screening: The MVP Study (MRI vs PSA)

  • Condition: Prostate Cancer
  • Intervention: Device: Multi-parametric MRI, Other: PSA testing
  • Study ID: NCT02799303
View Trial

Erythropoietin to Enhance Erection Recovery in Men Following Radical Prostatectomy

  • Condition: Prostate Cancer, Erectile Dysfunction
  • Intervention: Drug: Placebo, Drug: EPO
  • Study ID: NCT00737893
View Trial

A Phase II, Prospective Study of MRI in the Reclassification of Men Considering Active Surveillance in Prostate Cancer

  • Condition: Prostate Cancer
  • Intervention: Device: Multiparametric MRI, Procedure: Prostate biopsy
  • Study ID: NCT01858688
View Trial

Phase II Trial Assessing the Feasibility and Toxicity of Degarelix in Achieving Prostate Downsizing Prior to Treatment With Permanent Seed Prostate Brachytherapy

  • Condition: Prostate Cancer
  • Intervention: Drug: Degarelix, Drug: Degarelix
  • Study ID: NCT01446991
View Trial

Hypoxia and Stem Cell Content as Aggression Factors in Prostate Cancer

  • Condition: Prostate Cancer
  • Intervention: Drug: Pimonidazole
  • Study ID: NCT02095249
View Trial

Pilot Study of Whole Gland Salvage HDR Prostate Brachytherapy for Locally Recurrent Prostate Cancer

  • Condition: Prostate Cancer Recurrent
  • Intervention: Radiation: HDR brachytherapy
  • Study ID: NCT02560181
View Trial

A Pilot Study of 18F-DCFBC PET/CT in Prostate Cancer

  • Condition: Prostatic Neoplasms, Prostate Cancer
  • Intervention: Drug: 18F DCFBC
  • Study ID: NCT02190279
View Trial

A Randomized Controlled Trial Of AdV-tk + Valacyclovir Administered During Active Surveillance For Newly Diagnosed Prostate Cancer

  • Condition: Prostate Cancer
  • Intervention: Biological: aglatimagene besadenovec, Biological: placebo, Drug: valacyclovir
  • Study ID: NCT02768363
View Trial
E-Newsletters

Newsletter subscription

Free Daily and Weekly newsletters offered by content of interest

The fields of GU Oncology and Urology are rapidly advancing. Sign up today for articles, videos, conference highlights and abstracts from peer-review publications by disease and condition delivered to your inbox and read on the go.

Subscribe