99mTc-PSMA-I&Amp;S in Patients With Prostate Cancer: An Exploratory Biodistribution Study With Histopathology Validation


Condition: Prostate Carcinoma, Recurrent Prostate Carcinoma

Study Type: Interventional

Clinical Trials Identifier NCT 8-digits: NCT04857502

Sponsor: Jonsson Comprehensive Cancer Center

Phase: Early Phase 1

Eligibility:

  • Age: minimum N/A maximum N/A
  • Gender: Male

Inclusion Criteria:

  • Men with PCa (primary or recurrent disease)
  • Men who received a 68Ga-PSMA-11 positron emission tomography (PET)/computed tomography (CT) for staging or restaging
  • Men with evidence of lymph nodes (LNs)-positive disease on 68Ga-PSMA-11 PET/CT
  • Men who are scheduled for pelvic LN dissection (PLND)
  • Men who can provide oral and written informed consent
  • Men who can comply with study procedures

Exclusion Criteria:

  • Patients who started any PCa treatment between study enrollment and surgery
  • Technically inaccessible nodal location

View trial on ClinicalTrials.gov