Imaging Center COE

Seeking a Diagnosis with a Rising PSA - Jelle Barentsz

(Length of discussion - 9 minutes) Dr. Jelle Barentsz provides his perspective on treating a patient with a rising PSA and is seeking diagnosis options. During this discussion held at the Radiological Society of North America (RSNA) 2017 conference, he shares that he would not recommend a 12-core systematic biopsy because it is not targeted. 40% of patients with a trans-rectal ultrasound guided (T...

18F-Fluciclovine PET/CT Scanning in High Risk Primary Prostate Carcinoma - Trond Bogsrud

18F-Fluciclovine PET/CT Scanning in Patients With High Risk Primary Prostate Carcinoma - Trond Bogsrud (Length of discussion - 10 minutes) Dr. Trond Bogsrud discusses the performance of the investigational amino acid PET tracer fluciclovine F18 compared to histopathology which was retrospectively evaluated in patients with high risk primary prostate carcinoma to investigate whether fluciclovine F1...

Prediction of Prostate Cancer Specific Survival - The Prognostic Value of 11C-Acetate PET/CT- Jens Sorensen

(Length of Presentation: 9 min) Jens Sorensen, MD presents on the topic of the prognostic value of 11C-Acetate PET/CT. 11 C-Acetate PET/CT is strongly linked to the aggressiveness of prostate cancer (PCa) under experimental conditions. 11 C-Acetate PET/CT is a potential noninvasive biomarker of malignant lipogenesis in PCa, but its prognostic value is not known. The objective of this study was to...

RADAR II Group Recommendations - The Role of Therapeutic Layering

David Crawford, MD discusses with Thomas Keane, MD, the paper, RADAR II: The Role of Therapeutic Layering in Optimizing Treatment for Patients with Castration-Resistant Prostate Cancer, which was designed to offer recommendations on identification of disease progression, treatment management strategies, and suggestions on timing of initiating and discontinuing specific castration-resistant prostat...

Imaging Controversies in Prostate Cancer- Interview with Phillip Koo

Imaging Controversies for Assessing Localized and Advanced PCa, an Interview with Charles Ryan and Phillip Koo Presentation from the 2017 annual LUGPA meeting in Chicago, IL (Length of interview: 6 min) Dr. Phillip Koo talks with Charles Ryan, MD about imaging controversies when it comes to local and metastatic disease. He overviews his LUGPA 2017 presentation on local disease in a practical and c...

18F-DCFBC PET/CT with Multiparametric MRI and Histopathology - Liza Lindenberg

(Length of lecture ~ 8 minutes) Prostate-specific membrane antigen (PSMA) is over-expressed in prostate cancer, so it is a good target to use for diagnoses and treatment. 18F-DCFBC binds to the external domain of PSMA, so when it is used as a PET tracer it can be very helpful in improving imaging of localized and metastatic prostate cancer. The goal of this research is to asses the ability of 18F-...

The Additional Value of PET for MRI Guided Transrectal Prostate Biopsies - Morand Piert

(Length of lecture - 12 minutes) In this presentation Dr. Piert discusses the random aspects of standard extended-sextant ultrasound-guided biopsy and the study that was designed to assess targeted vs standard biopsy and the 2 approaches combined for the diagnosis of intermediate- to high-risk prostate cancer. These trial results are published in JAMA, "Comparison of MR/ultrasound fusion-guided bi...

Ga-68 PSMA Lyophilized Ready to Use Kit for Diagnosis of Prostate Cancer by PET/CT - Stephan Maus

(Length of lecture ~ 13 minutes) Stephan Maus discusses Ga-68 labeled prostate-specific membrane antigen (PSMA) whole body PET/CT scan cold kit for the detection of prostate cancer lesions. Specifically, cold kit procedures have been under intense investigation due to their shortened synthesis times, reduced error rates and eliminating expensive hardware, making it a reliable alternative. This pre...

What the Referring Clinician Needs to Know from Molecular Imaging in Prostate Cancer - Felix Feng

(Length of lecture ~ 16 minutes) Dr. Feng provides a brief overview of prostate cancer management and how molecular imaging approaches can help guide the clinical management of prostate cancer, noting that imaging physicians need to educate their clinical colleagues about capabilities and limitations of these imaging studies. Additional content on molecular imaging ASCO 2017: How Advances in Molec...

18F-Fluciclovine: A New Option for Biochemical Recurrence in Prostate Cancer - Trond V. Bogsrud

(Length of lecture ~ 15 minutes) Trond V. Bogsrud, MD presented "18F-Fluciclovine: A New Option for Biochemical Recurrence in Prostate Cancer” at the SNMMI 2016, detailing the uptake of fluciclovine (18F) as a PET imaging radiotracer in comparison to other PET tracers in patients with biochemically recurrent prostate cancer. Additional content on 18F - Fluciclovine Stepping Into the Light: "Radiol...

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