BACKGROUND: Catheter-associated urinary tract infection (CAUTI) is a common clinic problem.
The purpose of this study was to investigate recent trends in CAUTI in neurogenic bladder patients focusing on extended-spectrum β-lactamase (ESBL)-producing Escherichia coli.
METHODS: Isolates from the urine of neurogenic bladder patients with UTI were investigated. Nine strains of ESBL-producing E coli were assayed by molecular strain typing using the Diversilab system for repetitive-sequence-based polymerase chain reaction (rep-PCR).
RESULTS: E coli accounted for most of the bacteria (74.1% to 81.0%) that produced ESBLs. Rep-PCR data showed that 7 out of 9 ESBL-producing E coli belonged to the same typing group with high similarity (more than 97% similarity) and that this distribution corresponded with antibiotic resistance patterns.
CONCLUSION: ESBL producing E coli strains isolated from CAUTI patients could be discriminated by rep-PCR typing using the Diversilab system in consistent with antibiotic resistance patterns.
Takaba K, Shigemura K, Osawa K, Nomi M, Fujisawa M, Arakawa S. Are you the author?
Department of Clinical Laboratory, Hyogo Prefectural Rehabilitation Center, Kobe, Japan; Division of Urology, Department of Surgery Related, Kobe University Graduate School of Medicine, Kobe, Japan; Infection Control Team, Kobe University Hospital, Kobe, Japan; Infection Control Team, Kobe University Hospital, Kobe, Japan; Department of Urology, Hyogo Prefectural Rehabilitation Hospital, Kobe, Japan.
Reference: Am J Infect Control. 2014 Mar;42(3):e29-31.