Male Infertility
Male Factor Infertility Diagnoses, But Not Male Age, Significantly Affects the Yield of Usable Embryos in Donor Oocyte Cycles.
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To evaluate the impact of male age and male factor infertility on embryo suitability for transfer in IVF cycles in which female factor is controlled.
The national SART Clinic Outcome Reporting System (SART CORS) cycle data was used to evaluate the impact of male age and male factor infertility diagnosis on embryo suitability for transfer in cycles using non-identified donor oocytes.
Ultrasound localisation microscopy tracks testicular microvascular adaptations to endocrine function in male infertility.
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Testicular disorders, including male infertility and hypogonadism, are increasingly prevalent and current diagnostic tools have important limitations. The testicular microcirculation underpins testicular function.
Integrating yoga as a holistic intervention in male infertility management: improved sperm parameters and stress reduction: a case report.
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Male infertility, particularly severe oligozoospermia, presents a significant challenge in reproductive health, often associated with high oxidative stress and poor lifestyle practices. This case report highlights the potential therapeutic role of a structured yoga regimen in improving semen quality, reducing stress, and enhancing quality of life in a male with long-standing infertility.
Variants in ZZS Complex-Associated Genes TEX11 and M1AP Are Responsible for Male Infertility and Nonobstructive Azoospermia.
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Nonobstructive azoospermia (NOA) is the most severe form of male infertility, with genetic factors contributing to approximately 30% of cases. However, only a small fraction of all NOA cases can be explained by the current genetic findings.
Gene set enrichment analysis of curated monogenic loci highlights key pathways and multisystem involvement in male infertility.
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Male infertility affects approximately 10% of men globally, yet approximately 70% of cases lack a definitive genetic diagnosis. Next-generation sequencing has identified numerous monogenic causes, many of which are linked to broader systemic conditions.
Metabolic Reprogramming in Male Infertility: Mechanistic Integration and Translational Perspectives From Mouse Models.
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Spermatogenesis is a highly energy-dependent and tightly regulated differentiation process in the male reproductive system, characterized by dynamic, stage-specific metabolic adaptations during spermatogonial proliferation, meiosis and sperm maturation.
Lifestyle factors impact sperm microbiota and are associated with biological and clinical issues in infertile patients undergoing assisted reproductive technologies, a proof-of-concept study.
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Sperm microbiota originates from local (urogenital, intestinal, cutaneous) and partner microbiomes, influenced by sexual activity. Its composition and diversity may impact male fertility, but research remains limited.
Role of dynamic changes in human sperm heat shock protein A2 in male infertility.
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Male factors account for approximately 50% of infertility cases; however, the mechanisms underlying sperm dysfunction remain unclear. Heat shock protein A2 (HSPA2) is a biomarker associated with sperm fertilization; however, few studies have examined changes in its localization in vitro.
Impact of bacteriospermia on sperm DNA fragmentation: a narrative review.
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Male infertility remains a significant global challenge, with bacteriospermia increasingly recognized as a contributor to impaired reproductive function. Emerging evidence suggests that bacterial infections may induce sperm DNA fragmentation.
Endocrine Disruption and Male Fertility.
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Endocrine-disrupting chemicals affect nearly every human on the planet and are known to interfere with reproduction. Most studies have focused on gestational exposure effects in females. Emerging evidence indicates that preconception exposures in males can also impact pregnancy outcomes and offspring health.