Imaging Center COE

INDICATE Trial Seeks to Clarify Role of PET Scans in Prostate Cancer Recurrence - Neha Vapiwala

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Alicia Morgans interviews Neha Vapiwala about the innovative phase three INDICATE trial, supported by the ECOG-ACRIN Group and NCI designated cooperative groups. The trial focuses on patients with biochemical recurrence after prostatectomy, examining the impact of PET scans on treatment decisions. It categorizes patients based on PET scan results: those without detectable cancer outside the pelvis...

The 7th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer - Faina Shtern

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Phillip Koo converses with Faina Shtern who highlights that this year's Summit aims to bridge the significant gaps between the imaging community and clinical community. She emphasizes the future of prostate cancer diagnosis and treatment lies in the integration of multiple diagnostic methods such as MRI, molecular imaging, and genomic profiling. The 2023 Summit will introduce a multiomics panel fo...

PSMA PET's Influence on Prostate Cancer Studies - Jeremie Calais

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Phillip Koo talks with Jeremie Calais about the EMBARK trial and the impact of PSMA PET on patient population characterization. The discussion explores how the EMBARK trial began back in 2015 before the existence of PSMA PET and how its introduction has affected the understanding and definition of patient populations in prostate cancer studies. Calais explains how their team retrospectively looked...

Setting a Global Standard: Unveiling the New PSMA PET/CT Procedure Guideline - Wolfgang Fendler & Ken Herrmann

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Philip Koo discusses the newly updated PSMA PET/CT: Joint EANM, SNMMI procedure guideline, version 2.0, with its first and senior authors, Wolfgang Fendler and Ken Herrmann from Germany. The updated guideline, considered a landmark paper, integrates new ligands and types of imaging, consolidating information on PSMA imaging for different ligands and formalizing them as a class of ligands. It featu...

Tackling the Last Mile: A Major Component to Successfully Establish Radioligand Therapy - Ken Herrmann

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Phillip Koo welcomes Ken Herrmann to discuss Herrmann’s team's latest article, "Tackling the Last Mile: A Major Component to Successfully Established Radioligand Therapy," arguing the importance of 'the last mile' of treatment delivery in nuclear medicine. Drawing parallels with the logistics industry, Herrmann emphasizes the need for flawless delivery of therapy to patients, with patient awarenes...

Improving Appropriate Utilization of Imaging in Prostate Cancer Patients: A Discussion on the RADAR Articles - E. David Crawford

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David Crawford joins Phillip Koo in a discussion on the Radiographic Assessments for Detection of Advanced Recurrence (RADAR) articles, which aimed to improve the appropriate utilization of imaging in prostate cancer patients. The RADAR articles looked at three areas: biochemical failure, newly diagnosed disease, and castrate-resistant non-metastatic disease. They suggested appropriate triggers fo...

PYLARIFY PET Imaging: A Transformative Resource for Urologists and Radiologists - Michael Kipper

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Philip Koo interviews Michael Kipper about the peer-to-peer PYLARIFY reader assistance program. Aimed at educating healthcare providers in accurately reading and interpreting PYLARIFY scans, the program seeks to enhance patient care and harmonize reporting across institutions. Dr. Kipper emphasizes that this initiative is not meant for over-reading studies but to extend understanding of PYLARIFY r...

Unraveling Prostate Cancer Response: PSMA PET Sheds New Light on Treatment Effectiveness - Andrei Gafita & Wolfgang Fendler

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In a recent led by Phillip Koo, Andrei Gafita and Wolfgang Fendler provide valuable insights on their innovative research, demonstrating the potential of PSMA PET imaging as a response to therapy tool in prostate cancer. Their study highlights the inconsistencies between PSMA PET responders and PSA levels, with about 50% of patients exhibiting this discrepancy. They found that PSMA PET imaging may...

The Role of Imaging Before and After Diagnosis of Localized Prostate Cancer - Masoom Haider

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Phillip Koo speaks with Masoom Haider about the potential of radiomics and machine learning in prostate cancer diagnosis and treatment. Dr. Haider explains that radiomics quantifies information in medical images, such as MRIs, to extract valuable data that can be analyzed using machine learning techniques. This could lead to better risk profiles for patients and more precise treatment plans. Howev...

Smarter Screening In Prostate Cancer - Sigrid Carlsson

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Sigrid Carlsson joins Phillip Koo in a discussion on Smart Screening in Prostate Cancer, a session being highlighted at the upcoming 6th Global Summit on Precision Diagnosis and Treatment of Prostate Cancer taking place virtually September 22-24. The pair discuss challenges with screening today that require clinicians to be smarter about screening including the risk of overdiagnosis, incorporating...