Advanced Prostate Cancer COE

An Update on the PRONOUNCE Trial, Comparing the Occurrence of Major Adverse Cardiovascular Events in Patients with Prostate Cancer and Cardiovascular Disease - Susan Slovin

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Susan Slovin joins Alicia Morgans to provide an update on the PRONOUNCE trial, the first Phase III prospective trial comparing a GnRH antagonist with a GnRH agonist with the endpoints of major adverse cardiovascular events. It explores how cardiovascular disease is not only affecting our patient's wellbeing on androgen deprivation therapy but also gives us for the first time a lot of different end...

Understanding Differences in Outcomes of Men with Prostate Cancer Based on Race and Ethnicity - Christopher Logothetis

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Christopher Logothetis and Charles Ryan review key takeaways from Christopher Logothetis's Advanced Prostate Cancer Consensus Conference (APCCC 2019) presentation on Ethnicity and Prognosis of Prostate Cancer and the importance in understanding the differences in outcomes of individuals with the disease based on race and ethnicity. In his work Dr. Logothetis prepared for APCCC 2019, he presses the...

The Changing Landscape for Locally Advanced Prostate Cancer- Maria de Santis

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Maria de Santis and Chuck Ryan share a conversation on the rapidly changing landscape for the treatment of locally advanced prostate cancer. A focus of the discussion centers around the STAMPEDE data demonstrating benefit with the early use of abiraterone and the use of radiation. They also discuss the role of docetaxel in this evolving environment based on data from both STAMPEDE and CHAARTED dat...

Karmanos Cancer Institute's 9th Annual Cancer Symposium - Elisabeth Heath

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Elisabeth Heath from the Karmanos Cancer Institute shares details on the upcoming Karmanos Cancer Institute's 9th Annual Cancer Symposium taking place this October. In response to such high demand and attendance, this is the first year the Symposium has been expanded to include all cancer types in addition to prostate cancer. This year's agenda focuses on Progress in Cancer Care, Advocacy and Surv...

Imaging Modalities to Treat Node-Positive Disease - Interview with Declan Murphy

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Declan Murphy sits down with Alicia Morgans during the Advanced Prostate Cancer Consensus Conference (APCCC 2019) to discuss men who have node positive but nonmetastatic prostate cancer and how we think about approaching treatment and integrating new imaging modalities into that entire therapeutic paradigm. Two aspects of managing node positive men in regards to surgery were talked about including...

How to Treat Men with pN1 Prostate Cancer - Presentation - Alberto Bossi

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Alberto Bossi presented on the recommended treatment for men with pathological node-positive prostate cancer. These patients are becoming more common as surgery is being performed on a higher proportion of high-risk patients with positive nodes. Highlighting unanswered questions regarding the treatment of these patients following surgery, Dr. Alberto Bossi mentions several studies that have assess...

Disadvantages of PSMA PET/CT in Advanced Prostate Cancer Imaging Presentation - Ian Davis

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As a follow-up to Dr. Stefano Fanti’s presentation on the advantages of PSMA PET-CT imaging, Dr. Ian Davis from Melbourne discussed some of the pitfalls and disadvantages of PSMA PET-CT in advanced prostate cancer imaging. Biography: Professor Ian Davis, MB, BS, Ph.D., FRAC,P FAChPM, is a medical oncologist, cancer immunologist, clinician-scientist, and NHMRC Practitioner Fellow. He is Professor o...

Radiation Therapy Options for Men with Newly Diagnosed cN1 cM0 Prostate Cancer - Mack Roach

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Mack Roach presents on radiotherapy options for patients with clinically node-positive prostate cancer at the 2019 Advanced Prostate Cancer Consensus Conference (APCCC). Dr. Roach touches on areas such as the optimal candidate for salvage lymph node dissection (SLND) for nodal recurrence of prostate cancer, the role of adding ADT to radiotherapy, and the NRG/RTOG 9413 study which showed whole pelv...

How Best to Treat cN1 Prostate Cancer - Karim Fizazi

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Karim Fizazi summarizes how best to treat node-positive (cN+) prostate cancer patients at the Advanced Prostate Cancer Consensus Conference (APCCC 2019). There are over 20 randomized controlled trials in localized and advanced prostate cancer that have been published according to Dr. Fizazi, yet he notes, none have been published in the setting of node-positive prostate cancer. In this presentatio...

Ethnicity and Prognosis of Prostate Cancer - Christopher Logothetis

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Christopher Logothetis presents on the ethnicity and prognosis of prostate cancer during the Regional Care (Demographic and Environmental Factors) Session at the Advanced Prostate Cancer Consensus Conference the (APCCC 2019). Dr. Logothetis discusses the significant difference in the incidence and mortality of prostate cancer worldwide. There are greater differences in the incidence rates than in...