Time-Related Changes in Patient Reported Bladder Symptoms and Satisfaction after Spinal Cord Injury.

Increased time after spinal cord injury (SCI) is associated with a migration to bladder managements with higher morbidity such as indwelling catheter (IDC). Still it is unclear how this affects bladder-related quality of life (QoL). We hypothesized that time from injury (TFI) would be associated with changes in bladder management, symptoms, and satisfaction.

Cross-sectional analysis of time-related changes in patient-reported bladder management, symptoms, and satisfaction, using the Neurogenic Bladder Research Group SCI Registry. Outcomes included: Neurogenic Bladder Symptom Score (NBSS) and bladder-related satisfaction (NBSS-satisfaction). Multivariable regression was performed to assess associations between TFI and outcomes, adjusting for participant characteristics, injury specifics, and psychosocial aspects of health-related QoL. Participants with TFI <1 year were excluded and TFI was categorized 1-5 (reference), 6-10, 11-15, 16-20, and >20 years.

Of 1420 participants, mean age at injury was 29.7(SD13.4) years and mean TFI was 15.2(SD11.6) years. Participants grouped by TFI included 298 (21%) 1-5, 340 (24%) 6-10, 198 (14%) 11-15, 149 (10%) 16-20, and 435 (31%) >20 years. As TFI increased, clean intermittent catheterization (CIC) declined (55% 1-5 vs. 45% >20 years, p <0.001), and IDC increased (16% 1-5 vs. 21% >20 years, p <0.001). On multivariable analysis, increased TFI was associated with less bladder symptoms at >20 years from injury (-3.21 [CI-1.29,-5.14,p <0.001]) and better satisfaction (6-10 years -0.20 [CI-0.41,0.01,p=0.070], 11-15 years -0.36 [CI-0.60,-0.11,p=0.002], 16-20 years -0.59 [CI-0.86,-0.32,p <0.001], >20 years -0.85 [CI-1.07,-0.63, <0.001]).

After SCI, CIC decreases and IDC increases over time; however, increasing TFI is associated with reduced urinary symptoms, and improved bladder-related satisfaction.

The Journal of urology. 2021 Sep 22 [Epub ahead of print]

Odinachi Moghalu, John T Stoffel, Sean P Elliott, Blayne Welk, Chong Zhang, Angela Presson, Jeremy Myers

University of Utah, Salt Lake City, Utah, USA., University of Michigan, Ann Arbor, Michigan, USA., University of Minnesota, Minneapolis, Minnesota, USA., Western University, Ontario, Canada.

email news signup
SUFU MyBladder app