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Peyronie's disease (PD) is a heterogeneous disorder with the classical penile symptoms of plaque formation, penile pain, deviation, penile shortening and erectile dysfunction. The etiology is unknown. Microtraumatic lesions with the development of an inelastic fibrous scar formation at the level of the tunica albuginea are discussed as a trigger mechanism besides a questionable genetically linked atypical wound healing. A non-surgical etiological treatment is not possible although several conservative treatment regimens are applied. In the stable stage of the disease the surgical treatment of penile curvature is the primary surgical goal. Depending on the grade of the curvature, penile length, and erectile dysfunction, various types of corrective surgery can be carried out. This article provides an overview about the current state of the diagnostic work-up, conservative management and surgical treatment options.

Der Urologe. Ausg. A. 2018 Aug 16 [Epub ahead of print]

A Hauptmann, F M E Wagenlehner, T Diemer

Klinik und Poliklinik für Urologie, Kinderurologie und Andrologie, Universitätsklinikum Giessen und Marburg GmbH, Standort Giessen, Justus-Liebig-Universität Giessen, Rudolf-Buchheim-Str. 7, 35385, Giessen, Deutschland., Klinik und Poliklinik für Urologie, Kinderurologie und Andrologie, Universitätsklinikum Giessen und Marburg GmbH, Standort Giessen, Justus-Liebig-Universität Giessen, Rudolf-Buchheim-Str. 7, 35385, Giessen, Deutschland. .

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