Purpose: Our aim was to evaluate short term survival rates in renal transplant recipients from deceased donors, while focusing on recipients with diabetes mellitus background.
Materials and Methods: This is a longitudinal follow-up study based on national registry of recipients in Ministry of Health and Medical Education in Iran from 2010-11. Five hundred fifty-five recipients, 226 (40.8%) females and 328 (59.2%) males, were included in the study. Mean (± SD) age of the recipients was 39 ± 14 years. Of donors 18.4% were females and 81.6% were males. Age of the donors was 33 ± 14 years. All allograft recipients from deceased donors enrolled in the study. Short-term graft survival (1 year) was determined. Data regarding age, gender, background disease and cold ischemic time of recipients and donors were collected from the organ procurement units.
Results: Allografts were functioning in 499 (90.1%) of recipients after one year. Of recipients 38 (6.9%) died and rejection of transplanted kidney occurred in 17 (3.1%) cases. So, in 55 (9.9%) cases, allografts were not functioning. There were significant relationships between short term graft survival of donors' gender, age of recipients, cold ischemic time and level of clearance of creatinine of recipients.
Conclusion: In addition to cold ischemic time, graft survival can be affected by recipients' age. There are some other considerations and implications regarding the short term graft survival in renal transplantation from cadaver donors which are discussed in this paper.
Written by:
Nakhjavani M, Ghaemi F, Ravaghi H, Aghighi M, Ghaemi F. Are you the author?
Department of Endoctrinology, Tehran University of Medical Sciences, Vali'asr Hospital, Tehran, Iran; Ministry of Health and Medical Education, Tehran University of Medical Sciences, Tehran, Iran; Department of Health Services Management, Health Management and Economics Research Center, School of Health Management and Information Sciences, Iran University of Medical Science, Tehran, Iran; Management Center of Transplantation and Special Diseases, Tehran University of Medical Sciences, Tehran, Iran; Department of Microbiology, Islamic Azad University, Kerman Branch, Kerman, Iran.
Reference: Urol J. 2014 May 6;11(2):1474-7.
PubMed Abstract
PMID: 24807763
UroToday.com Renal & Vascular Diseases Section
