A nationwide assessment of the burden of urinary tract infection among renal transplant recipients - Abstract

Objective: Evaluate the prevalence and outcomes of urinary tract infection (UTI) among renal transplant recipients.

Methods: A secondary analysis of the Nationwide Inpatient Sample 2009-2011 was conducted. Survey-weighted multivariable regression analyses were used to examine the impact of UTI on transplant complications, total charges, and length of stay.

Results: A total of 1,044 renal transplant recipients, representing a population estimate of 49,862, were included in the study. UTI was most common in transplant recipients with hypertension (53%) and prevalence was noted to be 28.2 and 65.9 cases per 1,000 for men and women, respectively. UTI increased the likelihood of transplant complications (182% for men, 169% for women). Total charges were 28% higher among men as compared to 22% among women with UTI. Such infection also increased the length of stay by 87% among men and 74% among women.

Discussion: UTI in renal transplant recipients was associated with prolonged length of stay, total charges, and increased odds of transplant complications. Interventions to prevent UTI among such patients should be a priority area for future research and practice.

Written by:
Becerra BJ, Becerra MB, Safdar N.   Are you the author?
School of Public Health, Loma Linda University, Loma Linda, CA 92350, USA; William S. Middleton Memorial Veterans Hospital, Madison, WI 53705, USA; Department of Health Science and Human Ecology, California State University San Bernardino, San Bernardino, CA 92407, USA; Department of Medicine, University of Wisconsin, Madison, WI 53706, USA.

Reference: J Transplant. 2015;2015:854640.
doi: 10.1155/2015/854640

PubMed Abstract
PMID: 25810918

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