Infections

Recurrent Urinary Tract Infections are associated with Frailty in Older Adults

To understand the relationship between frailty, age and recurrent urinary tract infections (rUTIs).

The Timed Up and Go Test (TUGT), a measure of frailty, was administered to all adults ages ≥65 presenting to an academic non-oncologic urology practice from December 2015 to January 2018.

The Prevalence of Urinary Tract Infection Following Flexible Ureterenoscopy and The Associated Risk Factors

 To evaluate the risk factors for urinary tract infection (UTI) after retrograde intrarenal surgery (RIRS).

 A retrospective evaluation of the records of patients who underwent RIRS from January 2013 to September 2016 was performed.

Community-Acquired Urinary Tract Infection by Escherichia coli in the Era of Antibiotic Resistance

Urinary tract infections (UTIs) caused by Escherichia coli (E. coli) are the most common types of infections in women. The antibiotic resistance of E. coli is increasing rapidly, causing physicians to hesitate when selecting oral antibiotics.

Ureteral stents in urolithiasis

Ever since the ureteral stent design was fitted with a curl on both sides to prevent it from migrating up or down the ureter some 40 years ago, its use has gained tremendous momentum, aiding in the rise and evolution of endourology and has confidently kept its place in modern time urology.

Patient Distress in Women with Recurrent Urinary Tract Infections: How Can Physicians Better Meet Patients Needs?

Recurrent urinary tract infections are a common condition that can impact patients' quality of life. The purpose of this review is to summarize and analyze the literature regarding the distress that these infections can cause to patients and provide guidance to clinicians on how to improve care of these patients.

Naftopidil for the treatment of lower urinary tract symptoms compatible with benign prostatic hyperplasia

Benign prostatic hyperplasia (BPH) is a common condition in ageing men that may cause lower urinary tract symptoms (LUTS). Treatment aims are to relieve symptoms and prevent disease-related complications.

A Review of Cranberry Use for Preventing Urinary Tract Infections in Older Adults

Urinary tract infections (UTIs) are one the of the most common types of infections in adults older than 65 years of age. Preventing UTIs with prophylactic antibiotics increases the risk of side effects and microbial resistance, and is costly.

Genital Wart and Human Papillomavirus Prevalence in Men in the United States From Penile Swabs: Results From National Health and Nutrition Examination Surveys

Human papillomavirus (HPV) is a common sexually transmitted infection in the United States that can lead to both malignant (high-risk) and benign (low-risk) findings. These low-risk findings include both genital condyloma, anal warts, and adult or juvenile papillomatosis, which are directly attributable to subtypes HPV 6 and HPV 11.

Bacteruria

Excerpt

Bacteriuria is the presence of bacteria in the urine and can be classified as symptomatic or asymptomatic. A patient with asymptomatic bacteriuria is further defined as having colonization with one or more organisms in a urine specimen without symptoms or infection.

Participant experiences of clean intermittent self-catheterisation, urinary tract infections and antibiotic use on the ANTIC trial - A qualitative study

Recurrent urinary tract infections are a commonly reported problem in people who use clean intermittent self-catheterisation. Yet there is a lack of knowledge regarding both the impact on people's lives, the use of prophylactic anti-biotics and perceptions of patients on their use.

Laboratory diagnosis of urinary tract infections: Towards a BILULU consensus guideline

The BILULU study group consists of seven microbiologists of hospital laboratories located in the region of Flanders (Belgium). A major goal of the group is to standardize diagnostic microbiology procedures based on available evidence and, in the absence of evidence, based on general microbiological principles and expert opinion.

Efficacy and Safety of Finafloxacin versus Ciprofloxacin in the Treatment of Complicated Urinary Tract Infections: An Explorative Randomized Phase II Clinical Study

The broad spectrum C-8-cyano-fluoroquinolone finafloxacin displays enhanced activity at acidic conditions. This phase II clinical study compared efficacy and safety of finafloxacin and ciprofloxacin in patients with complicated urinary tract infection and/or pyelonephritis.

Urine Trouble: Should We Think Differently About UTI? - Beyond the Abstract

Urinary Tract Infection (UTI) is widely considered to be a result of pathogenic bacteria colonizing the sterile environment of the bladder. However, the recent discovery of resident communities of bacteria (microbiota) in the bladders of both women [1-9] and men [10-11] challenges this concept. If the bladder and thus urine are not normally sterile, then the definition of infection must move beyond the mere presence of bacteria. We believe that we must revisit the contemporary description of UTI by identifying its limitations: the language of UTI, testing for a UTI, an Escherichia coli-centric view of UTI, and a threshold-based diagnosis for UTI. As the science of the urinary microbiome moves forward, we much acknowledge each of these aspects of UTI or, as our title suggests, ‘urine trouble.’

Surviving Fournier's gangrene: Multivariable analysis and a novel scoring system to predict length of stay

There is no contemporary scoring system to predict hospital length of stay and morbidity in Fournier's gangrene. A retrospective study was conducted to formulate a scoring system to predict duration of hospitalization, resource utilization, need for reconstruction, morbidity and mortality.

Urine trouble: should we think differently about UTI?

Urinary tract infection (UTI) is clinically important, given that it is one of the most common bacterial infections in adult women. However, the current understanding of UTI remains based on a now disproven concept that the urinary bladder is sterile.

Trends in Antibiotic Resistance in Urologic Practice

The significant global upsurge in antimicrobial resistance, particularly among Enterobacteriaceae, represents a serious threat to health care systems. The implications for urologic practice are of particular concern.

GenomeDx to Distribute Pathnostics’ Guidance UGx Test for Urinary Tract Infection and Guidance PRx Test for Prostatitis

Truckee, CA (UroToday.com) GenomeDx Biosciences, a leader in the field of urologic genomics, and Pathnostics, a provider of comprehensive and dynamic pathology services, announced a strategic agreement for GenomeDx’s distribution of Pathnostics’ Guidance UGx and Guidance PRx. These molecular diagnostic tests for urinary tract infections (UTIs) and prostatitis, respectively, improve upon traditional urine culture by detecting the genomic sequence of pathogens, providing a faster and more comprehensive solution for physicians and their patients. 

Involvement of signal peptidase I in Streptococcus sanguinis biofilm formation

Biofilm accounts for 65-80 % of microbial infections in humans. Considerable evidence links biofilm formation by oral microbiota to oral disease and consequently systemic infections. Streptococcus sanguinis, a Gram-positive bacterium, is one of the most abundant species of the oral microbiota and it contributes to biofilm development in the oral cavity.

Non-surgical management of recurrent urinary tract infections in women

One in three women will experience a clinically significant urinary tract infection (UTI) by age twenty-four and almost half will have at least one in their lifetime. Recurrent UTIs (rUTIs) are defined as having greater than two infections in a 6-month period, or three infections over twelve months, with complete resolution for at least two weeks.

Stromal Cell-Derived Factor 1 Mediates Immune Cell Attraction upon Urinary Tract Infection

Urinary tract infection (UTI) is the most common type of bacterial infection in humans. Fifty percent of all women will experience at least one UTI in their lifetime, with uropathogenic Escherichia coli (UPEC) accounting for 80% of reported cases.