Video Lectures
State-of-the-industry video lectures by leading urology experts
Latest Videos

ORLANDO, FL USA (UroToday.com) - The relationship between obesity and high-risk clear cell type RCC is not clear. Karim Chamie and colleagues studied the association of obesity with lymphatic spread and survival in patients from an international phase III clinical trial which tested the efficacy of cG250 antibodies in patients with high risk for recurrence of high-risk clear cell RCC.

auaThe authors reviewed clinical and pathologic records of 864 patients from the phase III clinical trial. They assessed patient BMI in addition to other demographic status. BMI was stratified into widely accepted BMI groups. They then calculated for the association between BMI, severity of disease, and survival in patients with clear cell RCC.

They found that majority of patients were overweight and obese. Interestingly, they found that increasing BMI led to a decrease incidence of lymphatic spread in their cohort of patients. Furthermore, obesity was associated with improved disease-free and overall survival.

The authors concluded that in their cohort of patients, for those who had had nephrectomies for RCC, obesity was beneficial. This is a very interesting finding as previous belief has been that obesity is associated with higher risk of having kidney cancer. The results of the study may indicate that BMI is not a good indicator of kidney cancer. Taking into account the weight loss of patients is necessary to confirm the conclusions from the study, patients in the obese category may not have lost as much weight, a factor that is usually associated with worsening disease.

Presented by Karim Chamie, MD at the American Urological Association (AUA) Annual Meeting - May 16 - 21, 2014 - Orlando, Florida USA

Los Angeles, CA USA

Written by Garen Abedi, MD, University of California (Irvine), and medical writer for UroToday.com

 

Articles
Editor selected abstracts and commentaries
Clinical Trials
Searchable data base of currently enrolling clinical trials
Calendar
Upcoming urology industry events
February 24, 2018 / Charleston Marriott
Advances in Cancer Immunotherapy™ - Charleston, SC
February 24, 2018 /
2018 IUA Annual Meeting
February 26-27, 2018 / The Royal Marsden Hospital
MediSens – The European Medical Imaging Conference
February 27-March 3, 2018 /
SUFU 2018 Winter Meeting
March 1-3, 2018 / Omni Amelia Island Plantation Resort, Fernandina Beach, FL
75th Annual Meeting Mid-Atlantic Section of the American Urological Association
Journals
Print publications focusing on urological cancer treatments through original commentary & articles

Everyday Urology™ - Oncology Insights

From the Editor

Prostate Cancer and Prostatic Diseases

From the Editor

@UroToday