ORLANDO, FL USA (UroToday.com) - Multiparametric MRI (mp-MRI) is important in the detection of prostate cancer. Mohamed Abd-Alazeez presented results of his group's study on MRI imaging in which they evaluated the performance of various MRI sequences and their ability to detect prostate cancer. The study was comprised of a cohort of 37 men who had presented after prostate radiotherapy. The authors compared mp-MRI with T2-wighted, diffusion-weighted and dynamic contrast-enhanced imaging. Their cohort of patients were followed with subsequent prostate biopsies within 10 months of their imaging. Their comparison was drawn from rating scores of 2 independent radiologists.

auaThey found that 66% of hemi-glands of prostates were positive for cancer on template-prostate mapping biopsy. The authors also showed that detection was worse with T2-weighted imaging compared to mp-MRI, both in reader 1 and reader 2. The inter-rater reliability was also calculated, which is important in a study with two reviewers. The authors reported substantial agreement between the readers.

They concluded that mp-MRI is a more accurate method than T2-weighted imaging in detecting prostate cancer in patients who have already had radiation therapy for their tumors. The authors recommended that in a similar situation, when a T2 weighted sequence is used, high b value DWI or ADC map should be included as part of the imaging protocol. With the current study, given that the agreement is substantial between reviewers, it would be beneficial if the data from the two reviewers were combined, given that the primary goal was to compare the two different sequences of MRI. This study is timely as it brings up the idea of over diagnosis of prostate cancer. More accurate methods of detecting significant prostate cancer are needed to prevent unnecessary treatment.

Presented by Mohamed Abd-Alazeez, MD at the American Urological Association (AUA) Annual Meeting - May 16 - 21, 2014 - Orlando, Florida USA

London, United Kingdom

Written by Garen Abedi, MD, University of California (Irvine), and medical writer for UroToday.com

 

 

Calendar
Upcoming urology industry events
April 27-29, 2018 / European Society for Medical Oncology Update for Practising Oncologists
European Society for Medical Oncology Update for Practising Oncologists
May 14, 2018 / InterContinental Mark Hopkins Hotel
SITC Cancer Immune Responsiveness Workshop
May 16-17, 2018 / InterContinental Mark Hopkins Hotel
SITC Immuno-Oncology Biomarkers: State of the Art Workshop
May 17, 2018 / Moscone Convention Center North/South, San Francisco, CA
SAU 2018 Annual Meeting at the AUA
Journals
Print publications focusing on urological cancer treatments through original commentary & articles

Everyday Urology™ - Oncology Insights

From the Editor

Prostate Cancer and Prostatic Diseases

From the Editor