ORLANDO, FL USA (UroToday.com) - Multiparametic MRI (mp-MRI) provides reliable evaluation of focal areas and local staging of prostate cancer. It specifically shows extracapsular extension and seminal vesicle invasion. Francesco Porpiglia and colleagues wanted to evaluate the ability of this MRI method in identifying prostatic capsular invasion (PCI) by comparing it with histopathologic evaluation.

auaThe authors included 230 patients with prostate cancer who had preoperative MRI before their radical prostatectomy. They identified the location and extent of cancer for both MRI and pathological specimens. Tumor maps were also prepared for each case.

They found that 39 tumors were pT2a-b; 120 were pT2c; 46 were pT3a and 25 were pT3b. Mp-MRI was found to correctly identify lesions in greater than 90% of cases.

The authors concluded that MRI was accurate in its assessment of prostate cancer lesion characteristics and was similar to pathologic assessment results. They suggested that mp-MRI may be a necessary piece in evaluating patients with prostate cancer. It may be necessary to validate the technique of radiology readings as many radiologists have a challenging time reading the MRIs to make classifications of invasion of prostatic capsular invasion. Authors will need to include the radiologist’s method of assessing whether a particular patient’s image was positive for capsular invasion as it is not clear from the abstract that was presented.

Presented by Francesco Porpiglia, MD at the American Urological Association (AUA) Annual Meeting - May 16 - 21, 2014 - Orlando, Florida USA

Orbassano, Italy

Written by Garen Abedi, MD, University of California (Irvine), and medical writer for UroToday.com


Upcoming urology industry events
April 27-29, 2018 / European Society for Medical Oncology Update for Practising Oncologists
European Society for Medical Oncology Update for Practising Oncologists
May 14, 2018 / InterContinental Mark Hopkins Hotel
SITC Cancer Immune Responsiveness Workshop
May 16-17, 2018 / InterContinental Mark Hopkins Hotel
SITC Immuno-Oncology Biomarkers: State of the Art Workshop
May 17, 2018 / Moscone Convention Center North/South, San Francisco, CA
SAU 2018 Annual Meeting at the AUA
Print publications focusing on urological cancer treatments through original commentary & articles

Everyday Urology™ - Oncology Insights

From the Editor

Prostate Cancer and Prostatic Diseases

From the Editor