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urothelial cell carcinoma (UCC):

1. Etiology & Epidemiology - Upper Tract Cancers
Background: Upper urinary tract urothelial tumors involving the renal pelvis or ureter account for 5% to 7% of all renal tumors and about 5% of all urothelial tumors. Renal pelvic tumors are not ...
2. Prostate Cancer Grading & Staging Systems
 The clinical staging of prostate cancer uses pretreatment parameters to predict the extent of disease, for assessment of prognosis and to assist in decisions regarding appropriate treatment.  Pretreatment ...
3. Beyond the Abstract - Clinical and immunologic effects of intranodal autologous tumor lysate-dendritic cell vaccine with aldesleukin (interleukin 2) and IFN-{alpha}2a therapy in metastatic renal cell carcinoma patients, by Marc Ernstoff, MD
BERKELEY, CA (UroToday.com) - Immunotherapy with IL-2 for metastatic renal cancer continues to offer a minority of patients the potential of durable complete responses without additional treatments.
4. Beyond the Abstract - Vascular stapling of the inferior vena cava: Further refinement of techniques for the excision of extensive renal cell carcinoma with unresectable vena-caval involvement, by Samir Shirodkar, MD, and Gaetano Ciancio, MD, MBA
BERKELEY, CA (UroToday.com) - Management of advanced renal cell carcinoma remains an extremely difficult scenario in urologic oncology.
5. Beyond the Abstract - A case of bone, lung, pleural and liver metastases from renal cell carcinoma which responded remarkably well to zoledronic acid monotherapy, by Atsushi Mizokami, MD, et al.
BERKELEY, CA (UroToday.com) - Bone, lung, pleural and liver metastases from renal cell carcinoma (RCC) are common sites.
6. Beyond the Abstract - Detection of circulating tumor cells in peripheral blood of patients with renal cell carcinoma correlates with prognosis, by Karen Bluemke PhD, et al.
BERKELEY, CA (UroToday.com) - The investigation of disseminated tumor cells in the peripheral blood, so-called circulating tumor cells (CTCs), has come more in focus recently.
7. Beyond the Abstract - The expression of thrombospondin-1 and p53 in clear cell renal cell carcinoma: Its relationship to angiogenesis, cell proliferation and cancer specific survival, by Dragomir P. Zubac, MD, and Svein A. Haukaas, MD, PhD
BERKELEY, CA (UroToday.com) - Clear cell renal cell carcinoma (CCRCC) is the most prevalent of the subtypes of renal cell carcinoma (RCC).
8. Beyond the Abstract - Costs of managing adverse events in the treatment of first-line metastatic renal cell carcinoma: Bevacizumab in combination with interferon-a2a compared with sunitinib, by Gerald Mickisch, MD
BERKELEY, CA (UroToday.com) - The availability of novel and promising targeted therapies for the treatment of patients with metastatic renal cell carcinoma (RCC), such as bevacizumab plus interferon and ...
9. Beyond the Abstract - The potential clinical value of FDG-PET for recurrent renal cell carcinoma, by Koya Nakatani, MD
BERKELEY, CA (UroToday.com) - The potential clinical value of FDG-PET for recurrent renal cell carcinoma FDG-PET is applicable for staging or re-staging, and monitoring therapeutic response in several ...
10. Beyond the Abstract - Laparoscopic radical nephrectomy for renal cell carcinoma: Oncological outcomes at 10 years or more, by Andre Berger, MD
BERKELEY, CA (UroToday.com) - Key finding: Perioperative and surrogate oncologic outcomes were analyzed in the urological literature.
11. Beyond the Abstract - Therapeutic potential of adult bone marrow-derived mesenchymal stem cells in prostate cancer bone metastasis, by Diptiman Chanda, PhD, and Selvarangan Ponnazhagan, PhD
BERKELEY, CA (UroToday.com) - Adult bone marrow-derived mesenchymal stem cells (MSC) have been shown to inhibit tumor growth in various studies.
12. Beyond the Abstract - Absolute preoperative C-reactive protein predicts metastasis and mortality in the first year following potentially curative nephrectomy for clear cell renal cell carcinoma, by Viraj Master, MD and Tim Johnson, MD
BERKELEY, CA (UroToday.com) - Approximately 30% of patients with localized renal cell carcinoma (RCC) will proceed to develop metastases following potentially curative nephrectomy.
13. Beyond the Abstract - Total fluid and specific beverage intake and risk of renal cell carcinoma in Canada, by Jinfu Hu, MD
BERKELEY, CA (UroToday.com) - This is a large, nationwide, population-based investigation based on a widely used and validated food frequency questionnaire (FFQ).
14. Beyond the Abstract - Single institutional experience with nephron-sparing surgery for pathologic stage T3bNxM0 renal cell carcinoma confined to the renal vein, by James M. McKiernan, MD and Solomon L. Woldu, MD
BERKELEY, CA (UroToday.com) - Our study of nephron-sparing surgery in renal cell carcinoma (RCC) invading the segmental branches of the renal vein is consistent with the trend towards increased utilization ...
15. Beyond the Abstract - Comparison of the UCLA Integrated Staging System and the Leibovich score in survival prediction for patients with nonmetastatic clear cell renal cell carcinoma, by Min-Han Tan, MD, PhD
BERKELEY, CA (UroToday.com) - In our recent article published in Urology, we sought to select the optimal model for risk classification of the post-operative patient with localized renal cell carcinoma ...
16. Beyond the Abstract - Renal oncocytoma-are there sufficient grounds to consider surveillance following prenephrectomy histologic diagnosis, by Miki Haifler, MD, and Amnon Zisman, MD, MHA
BERKELEY, CA (UroToday.com) - Oncocytoma is a benign tumor originating from the distal tubule.
17. Beyond the Abstract - An update on targeted therapy in metastatic renal cell carcinoma, by Lombardi Giuseppe, MD and Zagonel Vittorina, MD
BERKELEY, CA (UroToday.com) - For many years the mainstay of treatment for metastatic renal cell carcinoma (RCC) was immunotherapy, with response rates of from 10% to 20%.
18. Beyond the Abstract - Efficacy and safety of nephron-sparing surgery, by Hendrik Van Poppel, MD
BERKELEY, CA (UroToday.com) - In our recent article published in International Journal of Urology, we reviewed the current evidence of efficacy and safety of nephron-sparing surgery (NSS) in the management ...
19. Beyond the Abstract - TRPV2 activation induces apoptotic cell death in human T24 bladder cancer cells: A potential therapeutic target for bladder cancer, by Takashi Ueda, PhD
BERKELEY, CA (UroToday.com) - Bladder carcinoma is the second most common malignancy of the urinary tract and nearly 90% of all primary tumors of the bladder are urothelial carcinomas (UCs).
20. Beyond the Abstract - The role of radiologic imaging and biopsy in renal tumor ablation, by Omar Ortiz-Alvarado, MD and J. Kyle Anderson, MD
BERKELEY, CA (UroToday.com) - Over recent years, it is clear that the incidence of renal cell carcinoma (RCC) is increasing.