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141. Beyond the Abstract - Development of metastatic and non-metastatic tumor lines from a patient's prostate cancer specimen-identification of a small subpopulation with metastatic potential in the primary tumor, by Dong Lin, Peter W. Gout, and Yuzhuo Wang
BERKELEY, CA (UroToday.com) - Prostate cancer is generally recognized as a multifocal disease.
142. Beyond the Abstract - Treatment with tyrosine kinase inhibitors in patients with metastatic renal cell carcinoma is associated with drug-induced hyperparathyroidism: A single center experience in 59 patients, by Philipp Ivanyi, MD and Viktor Grünwald, MD
BERKELEY, CA (UroToday.com) - Herein, the authors report on the development of a secondary hyperparathyroidism (sHPT) associated with tyrosine kinase inhibitor treatment, namely sunitinib and sorafenib, ...
143. Beyond the Abstract - Dual-color, break-apart FISH assay on paraffin-embedded tissues as an adjunct to diagnosis of Xp11 translocation renal cell carcinoma and alveolar soft part sarcoma, by MingHao Zhong, MD, PhD and Meera Hameed, MD
BERKELEY, CA (UroToday.com) - Our study validated a FISH (fluorescent in situ hybridization) assay as an adjunct to diagnosis of Xp11 translocation renal cell carcinoma (RCC), a group of neoplasms characterized ...
144. Beyond the Abstract - MicroRNA-125b suppresses the development of bladder cancer by targeting E2F3, by Tianxin Lin, MD
BERKELEY, CA (UroToday.com) - Urinary bladder cancer is the most common urological tumor in China
145. Beyond the Abstract - The role of endorectal magnetic resonance imaging in predicting extraprostatic extension and seminal vesicle invasion in clinically localized prostate cancer, by Hyun Moo Lee, MD, PhD
BERKELEY, CA (UroToday.com) - The use of MRI to evaluate the local extent of disease is not routinely recommended because of the low sensitivity and accompanying low cost-effectiveness of this modality. ...
146. Beyond the Abstract - Oncological outcomes of partial nephrectomy for multifocal renal cell carcinoma greater than 4 cm, by Gopal N. Gupta, MD
BERKELEY, CA (UroToday.com) - The management of renal cell carcinoma in patients with multifocal renal tumors and hereditary syndromes predisposing to formation of RCC is challenging.
147. Beyond the Abstract - HER-2/neu expression in prostate adenocarcinoma: A systematic review and meta-analysis, by Ary Serpa Neto, MD
BERKELEY, CA (UroToday.com) - In 2008, a group led by Prof. Marcos Tobias-Machado, initiated a research series involving the role of the human epidermal growth factor receptor extracellular domain (HER-2/neu) ...
148. Beyond the Abstract - Cytogenetic features, clinical significance and prognostic impact of type 1 and type 2 papillary renal cell carcinoma, by Alessandro Antonelli, MD and Nicola Arrighi, MD
BERKELEY, CA (UroToday.com) - Prognostic stratification between different histologic subtypes of renal carcinoma is a commonly accepted practice
149. Beyond the Abstract - Testosterone measurement in patients with prostate cancer, by Claude C. Schulman MD, PhD
BERKELEY, CA (UroToday.com) - Testosterone has been a key therapeutic target in prostate cancer for more than 60 years, and modern advances have enriched our understanding of the pathophysiological importance ...
150. Beyond the Abstract - Preoperative CTLA-4 blockade: Tolerability and immune monitoring in the setting of a presurgical clinical trial, by Bradley C. Carthon, MD, PhD and Padmanee Sharma, MD, PhD
BERKELEY, CA (UroToday.com) - Intravesical bacillus Calmette-Guerin (BCG) therapy has been approved for decades as the only immunomodulatory agent that treats superficial bladder cancer.
151. Beyond the Abstract - Nuclear roundness variance predicts prostate cancer progression, metastasis, and death: A prospective evaluation with up to 25 years of follow-up after radical prostatectomy, by Robert Veltri, PhD
BERKELEY, CA (UroToday.com) - Researchers at the Fisher Biomarker Biorepository Laboratory (FBBL) have been studying nuclear morphometry to characterize tissue biomarkers that predict prostate cancer (PCa) ...
152. Beyond the Abstract - HAL blue-light cystoscopy in high-risk nonmuscle-invasive bladder cancer-Re-TURBT recurrence rates in a prospective, randomized study, by Bogdan Geavlete, MD
BERKELEY, CA (UroToday.com) - Our study assesses three rather debatable subjects in bladder cancer: the high-risk patients, the photodynamic diagnostic, and the indications and results of Re-TURBT.
153. Beyond the Abstract - Metronomic administration of zoledronic acid and Taxotere combination in castration resistant prostate cancer patients: Phase I ZANTE trial, by Michele Caraglia, MD, PhD
BERKELEY, CA (UroToday.com) - Recently it was demonstrated that a 3-weekly schedule of docetaxel (DTX) and prednisone is the standard first-line chemotherapy for patients with hormone-refractory prostate ...
154. Beyond the Abstract - Estradiol suppresses tissue androgens and prostate cancer growth in castration resistant prostate cancer, by Bruce Montgomery, MD
BERKELEY, CA (UroToday.com) - Prostate cancer that is resistant to hormonal therapy is now thought to remain sensitive to hormonal manipulations that affect endocrine organs besides the testis.
155. Beyond the Abstract - Evaluation of B7-H3 expression as a biomarker of biochemical recurrence after salvage radiation therapy for recurrent prostate cancer, by Alexander S. Parker, PhD, et al.
BERKELEY, CA (UroToday.com) - Approximately one third of men who undergo radical prostatectomy (RP) to treat clinically localized prostate cancer will develop a detectable PSA within 10 years.
156. Beyond the Abstract - Inhibition of ADAM9 expression induces epithelial phenotypic alterations and sensitizes human prostate cancer cells to radiation and chemotherapy, by Sajni Josson, MD
BERKELEY, CA (UroToday.com) - ADAM9 (A Disintegrin and Metalloprotease 9) is a transmembrane and secreted protein that regulate cell phenotype and behavior.
157. Beyond the Abstract - Documenting the location of prostate biopsies with image fusion, by Peter L. Choyke, MD, et al.
BERKELEY, CA (UroToday.com) - Prostate cancer is the most common solid organ malignancy among men in the Western world.
158. Beyond the Abstract - DNA hypermethylation in papillary renal cell carcinoma, by Philipp Nuhn, MD
BERKELEY, CA (UroToday.com) - In our recent study published in BJU International, we investigated the pattern of DNA CpG island hypermethylation in papillary renal cell carcinoma (pRCC).
159. Beyond the Abstract - Androgen deprivation therapy for prostate cancer: Recommendations to improve patient and partner quality of life, by Richard Wassersug, PhD, et al.
BERKELEY, CA (UroToday.com) - Much has happened with the use of androgen deprivation to treat prostate cancer (PCa) patients since Charles Huggins first castrated a patient in order to alleviate the symptoms ...
160. Beyond the Abstract - STAMP1 Is both a proliferative and an antiapoptotic factor in prostate cancer, by Yang Jin, et al.
BERKELEY, CA (UroToday.com) - Prostate cancer is the most common non-cutaneous cancer among men and is the second leading cause of cancer deaths in men in Western countries.