Introductory editorial: Lifelong LUTS, a matter of transition?

The EPIC study has highlighted the prominence of nocturia as a crucial symptom of overactive bladder (OAB), intertwining OAB and nocturia with bladder, kidney, and brain functions.

Expert opinion, review.

To truly comprehend lower urinary tract symptoms (LUTS), we must delve into the interactions among these three systems, alongside their circadian rhythms.

The perception of LUTS is a result of the intricate interplay between bladder, brain, and kidney function, which may evolve across a lifetime due to the (dys)functionality of these organs.

Neurourology and urodynamics. 2024 Jan 30 [Epub ahead of print]

Karel Everaert, George Bou Kheir, Johan Vande Walle, Irina Verbakel, François Hervé, NOPIA Research Group

Department of Human Structure and Repair, Faculty of Medicine and Health Sciences, Ghent University Hospital, Ghent, Belgium., Department of Urology, Ghent University Hospital, Ghent, Belgium., Department of Pediatric Nephrology, Ghent University Hospital, Erknet-Center, Ghent, Belgium.