p53 Protein Transduction Therapy: Successful Targeting and Inhibition of the Growth of the Bladder Cancer Cells
Monday, 02 January 2006
Introduction: Virus-mediated gene therapy for bladder cancer has some problems, such as efficiency of gene delivery and safety issues. We have reported that poly-arginine peptide (11R) has the ability to increase protein transduction in cells. Here, we show that p53 protein transduction using 11R is useful for targeting to bladder tumors and suppressing the growth of bladder cancer cells.
read more
|
European Urology - Antitumor Activity of the Antimicrobial Peptide Magainin II against Bladder Cancer Cell Lines
Wednesday, 28 June 2006
Volume 50, Issue 1, Pages 141-147 (July 2006) Abstract - Objective: Magainin II belongs to a family of antimicrobial peptides and has been shown to exhibit antibiotic activity in a wide range of organisms.
read more
|
European Urology - Partially Degraded RNA from Bladder Washing is a Suitable Sample for Studying Gene Expression Profiles in Bladder Cancer
Thursday, 23 November 2006
Volume 50, Issue 6, Pages 1347-1356 (December 2006) Abstract - Objectives: To determine the impact of different levels of RNA degradation on gene expression measurements and to ascertain if the gene expression profile obtained from bladder washing (BW) correlates to that obtained from the related bladder tumour (BT).
read more
|
Lack of Prophylactic Effect of Incadronate on Skeletal Lesions Associated with Implants of Prostate Cancer
Monday, 02 January 2006
Objectives: To evaluate prophylactic effects of bisphosphonate (BP) on skeletal lesions induced by prostate cancer (CaP).
read more
|
Relationship of NKX3.1 and MYC Gene Copy Number Ratio and DNA Hypomethylation to Prostate Carcinoma Stage
Monday, 02 January 2006
Objective: High stage prostate cancers have been reported to frequently harbor chromosome 8 alterations and hypomethylation of LINE-1 retrotransposons. The potential of these parameters for molecular staging of prostate carcinoma was investigated.
read more
|
