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Editorials (April 2006)
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Are We Really Making an Advance in the Treatment of Metastatic Renal Cell Carcinoma?
Thursday, 06 April 2006
Renal cell carcinoma (RCC) is the most lethal of the common urologic malignancies with 40% of the patients eventually dying of cancer progression. Almost all of the patients presenting with metastatic RCC or who had progressed after initial treatment die because of their disease within a year. Until recently, not much could be offered to these patients except palliative measures. Systemic cytotoxic chemotherapy and radiotherapy are ineffective in this disease. The classical nonspecific immunotherapy with cytokines, interferon a (IFN-α), interleukin 2 (IL-2), their combination, or the triple treatment (IFN-α, IL-2, and 5-fluorouracil [5-FU]) gives overall response rates from 2% to 40% [1]. However, only a small subset of these patients show long-term response and cure is a rare event.
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Is Penile Enlargement an Ethical Procedure for Patients with a Normal-Sized Penis?
Monday, 03 April 2006
Yoram Vardi, Rambam Medical Center, Neuro-urology, Haifa, Israel The publication by Chi-Ying Li and coworkers entitled “Penile Suspensory Ligament Division for Penile Augmentation Surgery: Indications and Results” [1] gives us for the first time new information on the objective outcome and patients’ satisfaction from surgical procedures to increase penile length.
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Botulinum Toxin—New Mechanisms, New Therapeutic Directions?
Monday, 03 April 2006
Christopher Chapple, Anand Patel, Sheffield Teaching Hospitals NHS Trust, Urology Research Department, Royal Hallamshire Hospital, UK In 2002 the International Continence Society (ICS) published an updated standardisation report on the terminology that describes lower urinary tract function [1].
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Nomograms are More Meaningful than Severity-Adjusted Institutional Comparisons for Reporting Outcomes
Monday, 03 April 2006
Eric D. Hixson, The Quality Institute, Cleveland Clinic Health System, USAMichael W. Kattan, Quantitative Health Sciences, Cleveland Clinic Foundation, USAIt is becoming increasingly popular for medical institutions to report their medical outcomes by comparing them with other institutions. These comparisons often take the form of calculating a percentile ranking for an institution, comparing an outcome rate with a median or 90th percentile figure, or comparing observed with predicted outcome values assuming a peer institution. In most cases, these comparisons are risk-adjusted for an institution's case mix.
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Radical Prostatectomy: Open? Laparoscopic? Robotic?
Monday, 03 April 2006
Laurent Boccon-Gibod Hôpital Bichat, Clinique Urologique, Paris, FranceThis issue of European Urology offers two extensive reviews of laparoscopic radical prostatectomy (LRP) written by two famous urologists who have pioneered the technique, explored its different modalities, and become worldwide recognized experts in the field.
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The Start-Up of the Platinum Journal: A Fascinating Challenge
Monday, 03 April 2006
Francesco Montorsi Department of Urology, Universita’ Vita Salute San RaffaeleThe new Editorial Board of European Urology took over the guidance of the peer-review process of the Platinum Journal on September 1st 2005, following the 30 extraordinary years from Prof. Claude Schulman's office.
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