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SUFU 2008 Winter Meeting - POS #BS20 - Botulinum Toxin Type A Normalizes Alterations in Urothelial ATP and Nitric Oxide Release Induced by Chronic Spinal Cord Injury

Introduction and Objectives: The purpose of this paper was to simultaneously examine changes in urothelial ATP and nitric oxide (NO) release in normal and spinal cord injured (SCI) animals as well as in spinal cord injured animals treated with botulinum toxin type A (BoNT-A) and to correlate changes in transmitter release with functional changes in bladder contraction frequency and with efferent nerve function.

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