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Prostate Cancer

UroToday's Prostate Cancer section is a repository of the clinical publications, clinical trials and investigative science pertaining to the diagnosis and treatment of prostate cancer. Also available are conference coverage for all timely prostate cancer science, streaming media presentations, audio podcasts and downloadable slides from UroToday's slide library.

Online Urology & Urologic Oncology Journal
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Christopher P. Evans MD,
Associate Section Editor of Oncology/Prostate Cancer,
UroToday International Journal

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Editorial - Carbonic anhydrase IX expression in prostate cancer
Tuesday, 09 February 2010
BERKELEY, CA (UroToday.com) - Tumor hypoxia plays a role in tumor progression and chemotherapy resistance through reduced apoptosis, increased proliferation and angiogenesis. Hypoxic
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Molecular and biochemical effects of a kola nut extract on androgen receptor-mediated pathways - Abstract
Tuesday, 09 February 2010
Department of Environmental Toxicology, Southern University and A&M College, P.O. Box 9264, 108 Fisher Hall, Baton Rouge, LA 70813, USA.
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How costly is particle therapy? Cost analysis of external beam radiotherapy with carbon-ions, protons and photons - Abstract
Tuesday, 09 February 2010
Maastricht Radiation Oncology (MAASTRO Clinic), The Netherlands.
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Symptomatic response rates to testosterone therapy and the likelihood of completing 12 months of therapy in clinical practice - Abstract
Tuesday, 09 February 2010
Men's Health Boston, Division of Urology, Harvard Medical School, Boston, MA, USA.
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Survival benefit of radical prostatectomy in lymph node-positive patients with prostate cancer - Abstract
Tuesday, 09 February 2010
Munich Cancer Registry of the Munich Cancer Center, Department of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-University, Munich, Germany.
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Targeted therapeutic approaches for hormone-refractory prostate cancer - Abstract
Tuesday, 09 February 2010
Department of Medicine, Royal Marsden Hospital, Downs Road, Surrey SM2 5PT, UK.
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Pathogenesis of osteoblastic bone metastases from prostate cancer - Abstract
Tuesday, 09 February 2010
Osteo-oncology Center, Scientific Institute of Romagnolo for the Study and Cure of Tumors, Meldola, Italy.
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Decline of the red blood cell count in patients receiving androgen deprivation therapy for localized prostate cancer: Impact of ADT on insulin-like growth factor-1 and erythropoiesis - Abstract
Tuesday, 09 February 2010
Division of Urology, Department of Regenerative and Transplant Medicine, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.
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Focal positive surgical margins decrease disease-free survival after radical prostatectomy even in organ-confined disease - Abstract
Tuesday, 09 February 2010
Department of Urology, University of Michigan, Ann Arbor, Michigan.
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Radical prostatectomy for prostate cancer after ileal pouch-anal anastomosis offers oncologic control and sustains quality of life - Abstract
Tuesday, 09 February 2010
Department of Urology, Mayo Medical School and Mayo Clinic, Rochester, MN, USA.
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Beyond the Abstract - Detection rate and factors predictive the presence of prostate cancer in patients undergoing ultrasonography-guided transperineal saturation biopsies of the prostate, by Rafael Boscolo-Berto, MD
Monday, 08 February 2010
BERKELEY, CA (UroToday.com) - With regard to the prognostic factors predicting the diagnosis of prostate cancer, in our analysis, prostate volume was the unique clinical and pathological variable significantly associated with the incidence of prostate cancer in multivariate analysis.
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Prostate cancer treatment for economically disadvantaged men: A comparison of county hospitals and private providers - Abstract
Monday, 08 February 2010
Division of Urologic Oncology, Moores Comprehensive Cancer Center, University of California San Diego, La Jolla, California.
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Fatigue in hormone-naïve prostate cancer patients treated with radical prostatectomy or definitive radiotherapy - Abstract
Monday, 08 February 2010
Department of Clinical Cancer Research, The Norwegian Radium Hospital, Oslo University Hospital, Rikshospitalet, Oslo, Norway.
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Overall survival analysis of a phase II randomized controlled trial of a Poxviral-based PSA-targeted immunotherapy in metastatic castration-resistant prostate cancer - Abstract
Monday, 08 February 2010
Dana-Farber Cancer Institute, Harvard Medical School, Boston.
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Toxicity analysis of dose escalation from 75.6 Gy to 81.0 Gy in prostate cancer - Abstract
Monday, 08 February 2010
Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA.
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Role of cationic channel TRPV2 in promoting prostate cancer migration and progression to androgen resistance - Abstract
Monday, 08 February 2010
Institut National de la Santé et de la Recherche Médicale, U-800, Equipe labellisée par la Ligue Nationale contre le cancer; Université des Sciences et Technologies de Lille, Villeneuve d'Ascq, France.
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Sexual bother following radical prostatectomy - Abstract
Monday, 08 February 2010
Department of Psychiatry and Behavioral Sciences--Memorial Sloan-Kettering Cancer Center, NY 10021, USA.
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Carbonic anhydrase IX expression in prostate cancer - Abstract
Monday, 08 February 2010
Conway Institute of Biomolecular & Biomedical Research, University College Dublin School of Medicine and Medical Science, University College Dublin, Dublin, Ireland
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Prostate cancer therapy can increase heart risk factors
Friday, 05 February 2010
DALLAS, TX, USA (News Release) - February 1, 2010
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Potential effectiveness of pelvic floor rehabilitation treatment for postradical prostatectomy incontinence, climacturia, and erectile dysfunction: A case series - Abstract
Friday, 05 February 2010
University of Modena and Reggio Emilia-Department of Urology, Modena, Italy.
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The impact of positive surgical margins on mortality following radical prostatectomy during the prostate specific antigen era - Abstract
Friday, 05 February 2010
Department of Urologic Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
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Expression of Bcl-2, p53, and MDM2 in localized prostate cancer with respect to the outcome of radical radiotherapy dose escalation - Abstract
Friday, 05 February 2010
Academic Urology Unit, Institute of Cancer Research, Royal Marsden NHS Foundation Trust, Surrey.
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Prostate cancer: Comparison of 3D T2-weighted with conventional 2D T2-weighted imaging for image quality and tumor detection - Abstract
Friday, 05 February 2010
Department of Radiology, New York University Langone Medical Center, NY, USA.
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Health-related quality of life up to six years after (125)I brachytherapy for early-stage prostate cancer - Abstract
Friday, 05 February 2010
Departmentsof Radiation Oncology, University Medical Center Utrecht, Utrecht, The Netherlands.
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Management of prostate cancer recurrence after definitive radiation therapy. - Abstract
Friday, 05 February 2010
Department of Radiation Therapy, Maisonneuve-Rosemont Hospital, 5415 Bd de l'Assomption, Montreal, Quebec, Canada H1T 2M4.
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Editorial - Alterations in cholesterol regulation contribute to the production of intratumoral androgens during progression to castration-resistant prostate cancer in a mouse xenograft model
Friday, 05 February 2010
BERKELEY, CA (UroToday.com) - It is known that in castration-resistant prostate cancer (CRPC) the androgen receptor (AR) is expressed and remains active and prostate cancer (CaP) cells are able to produce their own supply of androgens.
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Spot scanning proton beam therapy for prostate cancer: Treatment planning technique and analysis of consequences of rotational and translational alignment errors - Abstract
Friday, 05 February 2010
University of Texas-M.D. Anderson Cancer Center, Houston, TX.
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Impact of ethnicity on primary treatment choice and mortality in men with prostate cancer: Data from CaPSURE - Abstract
Friday, 05 February 2010
Department of Urology and Winship Cancer Institute, Emory University, Atlanta, GA.
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Surgical treatment of stress incontinence in men - Abstract
Thursday, 04 February 2010
University of Toronto, Sunnybrook Health Sciences Centre, Room A309, 2075 Bayview Avenue, Toronto, ON M4N3M5 Canada.
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Tumor percent involvement predicts prostate specific antigen recurrence after radical prostatectomy only in men with smaller prostate - Abstract
Thursday, 04 February 2010
Division of Urologic Surgery and Duke Prostate Center, Department of Surgery, Duke University Medical Center, Durham, North Carolina.
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Focus on Prostate Cancer

Focus on Prostate Cancer condenses a selection of compelling and relevant science - on topic and chosen by the UroToday.com editorial staff.






Technology Centers Prostate Cancer - Prognostic Nomograms - by Ricardo Sanchez-Ortiz, MD EAU Position Statement on Screening for Prostate Cancer - News Release Anxiety and distress during active surveillance for early prostate cancer - by Roderick C.N. van den Bergh, MD, et al. Degarelix: A new approach for the treatment of prostate cancer - by Bo-Eric Persson, MD A 64-year-old man with low-risk prostate cancer: Review of prostate cancer treatment - by Sandip M. Prasad, MD and Martin G. Sanda, MD - Editor's Pick Apocrine Sweat Gland Obstruction by Antiperspirants Allowing Transdermal Absorption of Cutaneous Generated Hormones and Pheromones as a Link to the Observed Incidence Rates of Breast and Prostate Cancer in the 20th Century - by Kris G. McGrath, MD A Novel Communication Role for CYP17A1 in the Progression of Castration-Resistant Prostate Cancer - by Emma Tomlinson Guns, PhD Phase I/II Trial of Docetaxel and Concurrent Radiation Therapy in Localized High Risk Prostate Cancer (AGUSG 03-10) - by Michael Perrotti, MD, et al. A 1-Year, Open Label, Randomized Phase II Dose Finding Study of Degarelix for the Treatment of Prostate Cancer in North America - by Marc Gittelman, MD - Editor's Pick Management of the Side Effects of Androgen Deprivation Therapy in Men with Prostate Cancer - by Thomas W Flaig, MD Sexually Transmissible Infections and Prostate Cancer Risk - by Wen-Yi Huang, PhD, MSPH, et al. Serum Calcium and Incident and Fatal Prostate Cancer in the National Health and Nutrition Examination Survey - by Gary G. Schwartz, PhD, MPH - Editor's Pick Prostate cancer diagnosis and treatment after the introduction of prostate-specific antigen screening: 1986-2005 - by Christopher P. Evans, MD, FACS Periurethral suspension stitch during robot-assisted laparoscopic radical prostatectomy: Description of the technique and continence outcomes - by Christopher P. Evans, MD, FACS Duplicate presentations on prostate cancer at American Urological Association and European Association of Urology annual meetings - by Christopher P. Evans, MD, FACS High-Dose-Rate Brachytherapy for Localized Prostate Adenocarcinoma Post Abdominoperineal Resection of the Rectum and Pelvic Irradiation: Technique and Experience - by Christopher P. Evans, MD, FACS Impact of Surgeon and Hospital Volume on Outcomes of Radical Prostatectomy - by Christopher P. Evans, MD, FACS PCPT: Evidence That Finasteride Reduces Risk of Most Frequently Detected Intermediate- And High-Grade (Gleason Score 6 and 7) Cancer - by Christopher P. Evans, MD, FACS A Broader Role for 5ARIs in Prostate Disease? Existing Evidence and Emerging Benefits - by Christopher P. Evans, MD, FACS Patient Anxiety About Prostate Cancer Independently Predicts Early Initiation of Androgen Deprivation Therapy for Biochemical Cancer Recurrence in Older Men: A Prospective Cohort Study - by Christopher P. Evans, MD, FACS - Editor's Pick Predicting Prostate Cancer Risk Through Incorporation of Prostate Cancer Gene 3 - by Christopher P. Evans, MD, FACS HIV and Prostate Cancer: A Systematic Review of the Literature - by Christopher P. Evans, MD, FACS - Editor's Pick Obesity-Related Plasma Hemodilution and PSA Concentration among Men with Prostate Cancer - by Christopher P. Evans, MD, FACS - Editor's Pick Androgen Deprivation Therapy for Localized Prostate Cancer and the Risk of Cardiovascular Mortality - by Christopher P. Evans, MD, FACS Editor's Pick Patient Response to Total Intravenous Sedation (TIVS) for Outpatient Ultrasound-Guided Prostate Biopsy - by Ahmed Al-Sameraaii, MD, et al. A Four-Gene Expression Signature for Prostate Cancer Cells Consisting of UAP1, PDLIM5, IMPDH2, and HSPD1 - by Herbert A. Fritsche, PhD, et al. Peripheral Zone Sonographic Changes of the Prostate - by El-Housseiny Ismail Ibrahiem (El- Zalouey), MD, et al. Successful Early Prostate Cancer Screening by Three-Dimensional Color Doppler Imaging-Transrectal Ultrasound: A Prospective Study - by Walter Merkle, MD Mechanism of Neuroendocrine Differentiation in Prostate Cancer: BMP6-Macrophage-IL6 Loop via Obligatory Involvement of Both Smad-Dependent and -Independent Pathway - by Isaac Yi Kim, MD, et al. Secondary Therapy In Localized Prostate Cancer: Results From The Prostate Cancer Outcomes Study - by David F. Penson, MD, et al. Prostate Cancer Diagnosis in High Risk Patients The Finasteride Challenge Trial - by Bernd J Schmitz-Dräger, MD, et al. Key targets of hormonal treatment of prostate cancer. Part 2: The androgen receptor and 5α-reductase Robotic-assisted radical prostatectomy: A review of current outcomes Locally advanced prostate cancer: the role of surgical management Key targets of hormonal treatment of prostate cancer. Part 1: The androgen receptor and steroidogenic pathways Prostate Cancer: A Serious Disease Suitable for Prevention Prostate-Specific Antigen Kinetics in Localized and Advanced Prostate Cancer
SIU Satellite Symposium 2007 Advanced Prostate Cancer: Current Status, Controversies, and Future Directions By Fred Saad, MD, FRCS Bone Metastases Module By Edward Chow MBBS, PhD, FRCPC Accompanying Case Studies A 64 year old retired pharmacist presents to his primary care physician with complaints of urinary urgency and frequency of 6 months duration and of increasingly severe low back and right hip pain of 3 months duration. A 73 year old retired commericial fisherman was diagnosed 3 years ago with a Stage IV [Gleason 3 + 3(6)] prostate cancer with bone being the only site of metastases. A 55 year old woman presents to her primary care physician with occasional gross painless hematuria for 4 months. A 59 year old male had a diagnosis of renal cell carcinoma of the left kidney made 2 years ago after presenting with flank pain and hematuria.
9th International Prostate Forum - View Session Highlights Evaluation of the prostate cancer prevention trial risk calculator in a high-risk screening population - Session Highlight by Thomas J. Guzzo, MD, MPH from the AUA Mid-Atlantic Section 67th Annual Meeting What to do when the pathologist reports "positive margins" - Multimedia Lecture by William J. Catalona, MD from the AUA NY Section 107th Annual Meeting Open prostatectomy is best - Multimedia Lecture by William J. Catalona, MD from the AUA NY Section 107th Annual Meeting One year result of the retrourethral transobturator sling for the minimal-invasive treatment of male stress incontinence after radical prostatectomy - Slide Presentation by Christian G. Stief, MD at the Urological Research Society (URS) 25th Annual Meeting Prostate cancer detection using a novel computerized three-dimensional prostate biopsy template (Targetscan™): Results of a multicenter prospective data registry - Slide Presentation - Slide Presentation by Samir S. Taneja, MD at the Urological Research Society (URS) 25th Annual Meeting VI Maratona Urológica do Rio de Janeiro - View Prostate Cancer Session Highlights VI Maratona Urológica do Rio de Janeiro - View Prostate Cancer Slide Presentations American Society of Clinical Oncology (ASCO) 2009 Annual Meeting - View Prostate Cancer Session Highlights American Urological Association (AUA) 2009 Annual Meeting - View Prostate Cancer Session Highlights Post Prostatectomy Incontinence Study - SUFU 2009 - Highlight of a Presentation by Victor W. Nitti, MD Open, Laparoscopic and Robotic Prostatectomy: Much Ado About Nothing? - WUF 2009 - Lecture Presented by Christopher P. Evans, MD, FACS Society of Urologic Oncology (SUO) 9th Annual Winter Meeting - View Prostate Cancer Session Highlights Options in Prostate Cancer Surgery: Perineal Prostatectomy in the Age of Minimally Invasive Surgery - Masters in Urology 2008 - Slide Presentation Options in Prostate Cancer Surgery: Perineal Prostatectomy in the Age of Minimally Invasive Surgery - Masters in Urology 2008 - Slide Presentation Advances in the Treatment of Hormone Refractory Prostate Cancer - Masters in Urology 2008 - Session Highlight The American Society for Therapeutic Radiology and Oncology - 50th Annual Meeting - ASTRO 2008 - Prostate Cancer Abstracts American Society of Clinical Oncology - 44th Annual Meeting - ASCO 2008 - Prostate Cancer Abstracts The American Urological Association 2008 Annual Meeting - AUA 2008 Prostate Cancer Session Highlights Engineering and Urology Society - 23rd Annual Meeting - EUS 2008 - Prostate Cancer Abstracts